Reuniting overnutrition and undernutrition, macronutrients, and micronutrients

Diabetes/metabolism Research and Reviews
Miji KimJesse Roth

Abstract

Over-nutrition and its late consequences are a dominant theme in medicine today. In addition to the health hazards brought on by over-nutrition, the medical community has recently accumulated a roster of health benefits with obesity, grouped under "obesity paradox." Throughout the world and throughout history until the 20th century, under-nutrition was a dominant evolutionary force. Under-nutrition brings with it a mix of benefits and detriments that are opposite to and continuous with those of over-nutrition. This continuum yields J-shaped or U-shaped curves relating body mass index to mortality. The overweight have an elevated risk of dying in middle age of degenerative diseases while the underweight are at increased risk of premature death from infectious conditions. Micronutrient deficiencies, major concerns of nutritional science in the 20th century, are being neglected. This "hidden hunger" is now surprisingly prevalent in all weight groups, even among the overweight. Because micronutrient replacement is safe, inexpensive, and predictably effective, it is now an exceptionally attractive target for therapy across the spectrum of weight and age. Nutrition-related conditions worthy of special attention from caregivers includ...Continue Reading

References

Apr 1, 1979·Neurochemical Research·J R Cooper, J H Pincus
Jul 1, 1977·The Journal of Clinical Investigation·P M FarrellP A di Sant'Agnese
Jan 1, 1992·Biology of the Neonate·H J AminH G Parsons
Mar 25, 1992·Molecular and Cellular Biochemistry·W B WeglickiB F Dickens
Jul 1, 1991·Medicine·E B HealtonJ Lindenbaum
Jan 1, 1991·Vitamins and Hormones·A G Tahiliani, C J Beinlich
May 1, 1991·The American Journal of Clinical Nutrition·S N MeydaniS N Gershoff
Jan 1, 1990·Annals of the New York Academy of Sciences·R K Chandra, L Sudhakaran
Jul 19, 1990·The New England Journal of Medicine·G D Hussey, M Klein
Mar 1, 1990·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·N S Ross, M R Klein
Jan 1, 1988·Annual Review of Nutrition·D M Danks
Jun 30, 1988·The New England Journal of Medicine·J LindenbaumR H Allen
Oct 1, 1986·The American Journal of Clinical Nutrition·S F SuchyB Wolf
Feb 1, 1987·Metabolism: Clinical and Experimental·C M SmithC Steffen
Dec 1, 1974·Infection and Immunity·R H HeinzerlingD C Lueker
Aug 15, 1969·Annals of the New York Academy of Sciences·R WhangM MacDowell
Aug 15, 1980·Science·A W NormanG M Grodsky
Nov 1, 1984·The Journal of Clinical Endocrinology and Metabolism·E SamojlikN H Ertel
Sep 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·E AbeT Suda
Jun 30, 1995·Chemico-biological Interactions·M L HuY F Lin
Jan 1, 1995·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·F VaxmanJ F Grenier
Feb 1, 1994·The Annals of Pharmacotherapy·R WhangD D Whang
Apr 1, 1994·The International Journal of Eating Disorders·K Gupta, K Sivakumar
Aug 1, 1993·Nutrition Reviews·L C Rall, S N Meydani
Jun 15, 1996·American Journal of Epidemiology·A M TangA J Saah
Jan 1, 1997·Archives of Pediatrics & Adolescent Medicine·N H GoldenI R Shenker
May 30, 1998·Veterinary Research Communications·S I CeroneN J Auza
May 20, 1998·The American Journal of Clinical Nutrition·R UauyM Gonzalez
Sep 12, 1998·The Medical Journal of Australia·H G PeachS J Farish
Nov 3, 1998·Transplantation·D A HullettH F Deluca
Aug 31, 1999·The Proceedings of the Nutrition Society·H J Powers
Mar 22, 2000·Obstetrics and Gynecology·W L NelenT K Eskes

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Citations

Apr 14, 2019·Molecular Diversity·Toktam Shiebani Daloee, Farahnaz K Behbahani
Sep 26, 2020·Nutrients·Arantxa García-LegorretaBerenice Palacios-González
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lara R S FonsecaSílvia Socorro

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