Reversal of ophthalmic artery flow as a predictor of intracranial hemodynamic compromise: implication for prognosis of severe carotid stenosis

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
C-L TsaiG-S Peng

Abstract

High-grade cervical carotid stenosis (70-99%) or occlusion often accompanies reversed ophthalmic artery flow (ROAF), but its potential clinical significances remain poor understood. This study assessed ROAF and the related variables caused by carotid hemodynamic compromise in patients with unilateral severe cervical carotid stenosis. The study consisted of 200 patients diagnosed as unilateral high-grade cervical carotid stenosis/occlusion using ultrasonography. The hemodynamic parameters of 152 patients, excluding 48 with cervical carotid occlusion, were compared based on the presence of ROAF. Out of 200 patients, 159 underwent brain magnetic resonance imaging and were analysed for risk factors impacting functional outcomes including ROAF. The patients (n = 48) with internal carotid artery occlusion had significantly higher incidence (62.5%) of ROAF compared with that of 25.0% in those patients (n = 152) with unilateral high-grade carotid stenosis (P < 0.001). In ROAF patients (n = 38) with the unilateral high-grade stenosis, a significant retrobulbar arteries hemodynamic difference was observed between the stenotic and non-stenotic vessels. The patients (n = 159) with history of stroke (P = 0.035), ROAF (P = 0.023) and intracr...Continue Reading

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Citations

Nov 14, 2014·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A H V Schapira
Dec 17, 2015·Journal of the American Heart Association·Yueh-Feng SungGiia-Sheun Peng
Aug 4, 2016·Stroke; a Journal of Cerebral Circulation·Yueh-Feng SungGiia-Sheun Peng
Apr 4, 2017·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Tetsuro SekineShin-Ichiro Kumita

Related Concepts

Blood Flow Velocity
Cerebrovascular Circulation
Hemodynamics
Magnetization Transfer Contrast Imaging
Structure of Ophthalmic Artery
Retrospective Studies
Tomography, X-Ray Computerized Axial
Nested Case-Control Studies
Internal Carotid Artery Stenosis
Perfusion Magnetic Resonance Imaging

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