Reversal symmetries for cyclic paths away from thermodynamic equilibrium

Physical Review. E
John W Biddle, Jeremy Gunawardena

Abstract

If a system is at thermodynamic equilibrium, an observer cannot tell whether a film of it is being played forward or in reverse: any transition will occur with the same frequency in the forward as in the reverse direction. However, if expenditure of energy changes the rate of even a single transition to yield a nonequilibrium steady state, such time-reversal symmetry undergoes a widespread breakdown, far beyond the point at which the energy is expended. An explosion of interdependency also arises, with steady-state probabilities of system states depending in a complicated manner on the rate of every transition in the system. Nevertheless, in the midst of this global nonequilibrium complexity, we find that cyclic paths have reversibility properties that remain local, and which can exhibit symmetry, no matter how far the system is from thermodynamic equilibrium. Specifically, given any cycle of reversible transitions, the ratio of the frequencies with which the cycle occurs in one direction versus the other is determined, in the long-time limit, only by the thermodynamic force on the cycle itself, without requiring knowledge of transition rates elsewhere in the system. In particular, if there is no net energy expenditure on the c...Continue Reading

References

Apr 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·T L Hill, Y D Chen
Oct 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·J J Hopfield
Apr 3, 1995·Physical Review Letters·G Gallavotti, E G Cohen
Apr 24, 2002·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·G E Crooks
Aug 9, 2008·Proceedings of the National Academy of Sciences of the United States of America·Yuhai Tu
Mar 15, 2011·The European Physical Journal. E, Soft Matter·U Seifert
Sep 11, 2013·Bulletin of Mathematical Biology·Inomzhon Mirzaev, Jeremy Gunawardena
Oct 10, 2013·The FEBS Journal·Jeremy Gunawardena
Dec 7, 2013·Chemical Society Reviews·H Peter Lu
Sep 16, 2015·Proceedings of the National Academy of Sciences of the United States of America·Vincent J HilserHesam N Motlagh
Apr 30, 2016·Science·Christopher BattleFred C MacKintosh
Jul 2, 2016·Cell·Javier EstradaJeremy Gunawardena
Aug 17, 2018·Physical Review. E·Felix WongJeremy Gunawardena
Sep 9, 2018·Proceedings of the National Academy of Sciences of the United States of America·Felix WongJeremy Gunawardena
Dec 28, 2019·Proceedings of the National Academy of Sciences of the United States of America·Qiong Liu, Jin Wang
May 7, 2020·Annual Review of Biophysics·Felix Wong, Jeremy Gunawardena

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Citations

May 7, 2020·Annual Review of Biophysics·Felix Wong, Jeremy Gunawardena

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