Reversed shoulder arthroplasty leads to significant histological changes of the deltoid muscle: a prospective intervention trial.

Archives of Orthopaedic and Trauma Surgery
Matthias KochStefan Greiner

Abstract

Reverse shoulder arthroplasty (RSA) shows promising short- and mid-term results in cuff tear arthropathy. However, functional impairments are described in long-term findings. Micromorphological changes in the periarticular musculature could be in part responsible for this, but have not yet been analysed. Thus, histological changes of the deltoid muscle and their association to the functional outcome were evaluated in this study. A total of 15 patients treated with RSA were included in this prospective study. Functional outcome was assessed using the Constant Score (CS) and the DASH (disabilities of the arm, shoulder and hand) Score before RSA and after a mean follow-up of 12 months. Deltoid muscle biopsies were harvested intraoperatively and 12 months postoperatively. Mean deltoid muscle fibre area (MMFA) was calculated histologically after haematoxylin-eosin staining. Postoperative shoulder function significantly improved within 12 months (CS: Δ 37.4 ± 22.6, p = 0.001; DASH: Δ 27.1 ± 29.1, p = 0.006). The MMFA significantly decreased (p = 0.02), comparing the results from the intraoperative biopsy (MMFA: 8435.8 µm2, SD ± 5995.9 µm2) to the 12 months biopsy (MMFA: 5792. µm2, SD ± 3223.6 µm2). No correlation could be found betwe...Continue Reading

References

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Nov 10, 2009·Archives of Orthopaedic and Trauma Surgery·Stefan H GreinerPatrick Asbach
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Jul 7, 2011·Clinical Orthopaedics and Related Research·Paul M Grammont, Emmanuel Baulot
May 11, 2015·Journal of Shoulder and Elbow Surgery·Ryan W SimovitchJustin C Kearse
Jul 5, 2016·Journal of Shoulder and Elbow Surgery·Christian FischerFelix Zeifang

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