Reversibility of brain lesions in a case of Neuro-Behçet's disease studied by MR diffusion.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Luisa VuoloLuca Roccatagliata

Abstract

Behçet's disease is a multisystem disorder first described in 1937 as a triad of oral and genital ulcerations and uveitis. The etiology is unknown. Involvement of the central nervous system (CNS) occurs in 10-25% of patients. Neuro-Behçet's disease (NBD) can be classified as: (1) parenchymal, with a predilection for brainstem, basal ganglia and thalami involvement, subcortical white matter damage, spinal cord lesions, and meningoencephalitic presentations; (2) vascular, which usually affects major intracranial vessels with frequent involvement of the venous sinuses, cerebral veins and rarely intracranial arteries. Even if not constantly demonstrated in the CNS a vasculitic process involving small blood vessels, including venules, is regarded as an important pathological feature. We describe the case of a patient with NBD studied with conventional and diffusion weighted MR imaging.

Citations

Mar 27, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Yin-Yin XieHong-Mei Meng

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