Reversible cerebral vasoconstriction in Guillain-Barré syndrome

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Diana Y WeiP Alan Barber

Abstract

We present a 51-year-old woman with clinical and neurophysiological evidence of Guillain-Barré syndrome (GBS) who developed a generalised headache and autonomic dysfunction with sinus tachycardia, hypertension, gastrointestinal motility symptoms and urinary retention. MRI/MRA demonstrated cerebral vasoconstriction and a small convexity subarachnoid haemorrhage which resolved after 3 months. Reversible cerebral vasoconstriction syndrome (RCVS) is characterised by headache, focal neurological deficits or seizures, and reversible cerebral vasoconstriction. To our knowledge, this is the first reported case of RCVS complicating autonomic dysfunction in GBS. This case depicts a rare complication of a common condition and also sheds light on the potential mechanism of RCVS. Neurologists should be aware that autonomic dysfunction can lead to RCVS in GBS.

References

Oct 14, 2008·Lancet Neurology·Pieter A van DoornBart C Jacobs
Feb 27, 2010·The Journal of Headache and Pain·Bengt Edvardsson, Staffan Persson
Dec 24, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·Teddy Y WuP Alan Barber
Sep 22, 2012·Lancet Neurology·Anne Ducros

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Citations

Jul 1, 2015·Current Pain and Headache Reports·Constantine FarmakidisSteven Herskovitz
Oct 21, 2015·Hypertension·Gernot PichlerJosep Redon
Sep 19, 2019·Clinical Medicine : Journal of the Royal College of Physicians of London·Boby Varkey Maramattom

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