Reversible cerebral vasoconstriction syndromes.

Current Treatment Options in Cardiovascular Medicine
Richard A Bernstein

Abstract

Reversible cerebral vasoconstriction syndromes (RCVS) comprise a set of conditions having in common the apoplectic onset of headache mimicking subarachnoid hemorrhage, focal or multifocal neurologic deficits with a predilection for visual processing disorders, multifocal vasoconstriction on cerebral angiography, noninflammatory spinal fluid, and a generally benign prognosis. RCVS may occur in the setting of the puerperium, after intracranial surgery, in association with prescription or illicit drug use, in migraineurs, or without a clear trigger. Distinction from central nervous system vasculitis is important and is often possible using routine clinical assessment, without brain biopsy. No treatments are of proven value in RCVS. Empiric treatments include the use of calcium channel blockers, steroids, induced hypertension or blood pressure lowering, and rarely endovascular therapy. The key to successful management is accurate diagnosis and cognizance of the tendency of RCVS to resolve without long-term immunosuppressive treatment.

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Citations

Jul 28, 2007·Neurocritical Care·Christopher NickeleRichard A Bernstein
Sep 21, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·K KoopmanP C A J Vroomen
Nov 21, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Zhao YinAiwu Zhang
Mar 17, 2012·AJNR. American Journal of Neuroradiology·C P MarderK R Fink
Sep 24, 2008·The Journal of Headache and Pain·K KoopmanG J Luijckx

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