Reversible collapse of brushlike macromolecules in ethanol and water vapours as revealed by real-time scanning force microscopy

Chemistry : a European Journal
M O GallyamovMartin Möller

Abstract

Environment-controlled scanning force microscopy allowed us to study adsorption and desorption of single poly(methacrylate)-graft-poly(n-butyl acrylate) brush molecules on mica in real time. The molecules transform reversibly from a two-dimensional, extended wormlike state to a compact globular state. The dynamics of the conformational transition was sufficiently slow in order to allow its observation by scanning force microscope in real time. The reversible transformation is effected by coadsorption of water or ethanol, the latter introduces the collapse. Adsorbing ethanol and water from the vapour atmosphere results in a change of the surface properties of mica, either favouring adsorption or desorption of the graft polymer. When the extended, tightly adsorbed poly(n-butyl acrylate) brush molecules are exposed to ethanol vapour, the macromolecules swell and contract to form compact globules. Exchanging the ethanol vapour to a humid atmosphere caused the molecules to extend again to a wormlike two-dimensional conformation. Coexistence of collapsed and extended strands within the same molecule indicates a single-molecule first-order transition in agreement with observations on Langmuir films previously reported.

References

Aug 11, 1992·Nucleic Acids Research·Y L LyubchenkoS M Lindsay
Aug 1, 1997·Nucleic Acids Research·D D DunlapL Monaco
Apr 29, 1998·FEBS Letters·Y F DryginI V Yaminsky
Jun 10, 1998·Nucleic Acids Research·H G HansmaD Kwoh
Apr 2, 1999·Nucleic Acids Research·Y FangJ H Hoh
Jul 3, 1999·Nucleic Acids Research·K B ThurmondK L Wooley
Oct 13, 1999·FEBS Letters·Y Fang, J H Hoh
Oct 21, 1999·Biochemistry·R GolanH G Hansma
Nov 17, 2001·Biomacromolecules·S V MikhailenkoK Yoshikawa
Nov 7, 2002·Journal of the American Chemical Society·Anton KiriyManfred Stamm
Feb 19, 2003·Accounts of Chemical Research·Kazuaki Furukawa
Apr 17, 2003·Journal of the American Chemical Society·Jiro Kumaki, Takeji Hashimoto

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Citations

Jul 5, 2016·Chemistry : a European Journal·Priyanka Dey, Emad L Izake
Jun 2, 2005·Chemical Communications : Chem Comm·Doreen EckhardtHans G Börner
Oct 22, 2009·Physical Chemistry Chemical Physics : PCCP·Marat O GallyamovMartin Möller
Oct 18, 2011·Beilstein Journal of Nanotechnology·Konstantin I PopovIgor I Potemkin
May 19, 2011·Macromolecular Rapid Communications·Marat O Gallyamov
Apr 15, 2008·Soft Matter·Mukesh Kumar VyasManfred Stamm
Mar 20, 2007·Soft Matter·Hans G Börner, Helmut Schlaad
Jan 23, 2009·Journal of the American Chemical Society·Youyong XuAxel H E Müller
May 28, 2021·The Journal of Physical Chemistry. B·Bin Zhao
Mar 9, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Ahmed MourranMartin Moeller

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