Reversible logic gates based on enzyme-biocatalyzed reactions and realized in flow cells: a modular approach

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry
Brian E Fratto, Evgeny Katz

Abstract

Reversible logic gates, such as the double Feynman gate, Toffoli gate and Peres gate, with 3-input/3-output channels are realized using reactions biocatalyzed with enzymes and performed in flow systems. The flow devices are constructed using a modular approach, where each flow cell is modified with one enzyme that biocatalyzes one chemical reaction. The multi-step processes mimicking the reversible logic gates are organized by combining the biocatalytic cells in different networks. This work emphasizes logical but not physical reversibility of the constructed systems. Their advantages and disadvantages are discussed and potential use in biosensing systems, rather than in computing devices, is suggested.

References

May 29, 2003·Journal of the American Chemical Society·Milan N Stojanović, Darko Stefanović
Jan 26, 2006·Proteins·Ron Unger, John Moult
May 23, 2007·Nature Biotechnology·Keller RinaudoYaakov Benenson
Oct 26, 2007·Lab on a Chip·Michael W ToepkeDavid J Beebe
Jun 28, 2008·Chemical Reviews·Konrad Szaciłowski
Jul 25, 2008·Nature·A Prasanna de Silva
Jul 26, 2008·Nature Nanotechnology·A Prasanna de Silva, Seiichi Uchiyama
Apr 10, 2009·The Journal of Physical Chemistry. B·Vladimir PrivmanEvgeny Katz
Jun 26, 2009·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Patricia RemónUwe Pischel
Jun 30, 2009·Molecular BioSystems·Yaakov Benenson
Nov 12, 2009·The Journal of Physical Chemistry. B·Jian ZhouEvgeny Katz
Jan 27, 2010·Angewandte Chemie·Uwe Pischel
Feb 26, 2010·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Javier Cervera, Salvador Mafé
Apr 27, 2010·Chemical Society Reviews·Evgeny Katz, Vladimir Privman
Oct 5, 2010·The Journal of Physical Chemistry. B·Vladimir PrivmanEvgeny Katz
Oct 26, 2010·Nature Nanotechnology·Renjun PeiMilan N Stojanovic
Nov 5, 2010·Nature Nanotechnology·Vladimir Privman
Jan 5, 2011·Chemical Communications : Chem Comm·Zhongjian LiLargus T Angenent
May 4, 2011·Chemistry : a European Journal·Patricia RemónJoakim Andréasson
May 14, 2011·Journal of the American Chemical Society·Joakim AndréassonDevens Gust
Jul 22, 2011·Nature·Lulu QianJehoshua Bruck
Aug 5, 2011·Nature Nanotechnology·Yaakov Benenson
Jun 5, 2012·Analytical Chemistry·Evgeny KatzJan Halámek
Jun 13, 2012·Nature Reviews. Genetics·Yaakov Benenson
Jun 13, 2012·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Uwe PischelVânia F Pais
Aug 31, 2012·Chemical Communications : Chem Comm·Mary Anitha ArugulaZhen He
Dec 14, 2012·Proceedings of the National Academy of Sciences of the United States of America·Ron OrbachItamar Willner
Jun 5, 2013·The Journal of Physical Chemistry. B·Vladimir PrivmanEvgeny Katz
Jun 29, 2013·Chemical Communications : Chem Comm·Kevin MacVittieEvgeny Katz
Aug 1, 2010·IEEE Transactions on Biomedical Circuits and Systems· Yang Zhao, Krishnendu Chakrabarty
Sep 28, 2013·Analytical Chemistry·Karen ScidaRichard M Crooks
Mar 8, 2014·The Analyst·Fiona MoseleyEvgeny Katz
Apr 22, 2014·Analytical and Bioanalytical Chemistry·Nataliia GuzEvgeny Katz
May 31, 2014·Accounts of Chemical Research·Milan N StojanovicSergei Rudchenko
Sep 2, 2014·Chemical Communications : Chem Comm·Brian E FrattoEvgeny Katz
Sep 16, 2014·Scientific Reports·N TakeuchiN Yoshikawa

❮ Previous
Next ❯

Citations

Jan 11, 2016·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Evgeny Katz, Brian E Fratto
Jun 2, 2015·Chemical Communications : Chem Comm·Chunyang ZhouErkang Wang
Apr 3, 2016·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Brian E FrattoEvgeny Katz
May 6, 2016·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Nataliia GuzEvgeny Katz
Jan 27, 2017·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Mackenna L WoodVladimir Privman
Feb 28, 2017·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Evgeny Katz
Oct 26, 2018·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Evgeny Katz
Nov 23, 2019·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Evgeny KatzArtem Melman
Dec 3, 2016·Analytical and Bioanalytical Chemistry·Evgeny KatzMichael J Schöning
Jun 25, 2019·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Yaroslav FilipovEvgeny Katz
Jul 27, 2017·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Yaroslav FilipovEvgeny Katz
Aug 17, 2020·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Klaudia KaniewskaEvgeny Katz
Jul 27, 2021·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Daniel Massana RoqueroEvgeny Katz
Dec 4, 2019·ACS Applied Materials & Interfaces·Madeline MasiEvgeny Katz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry
Patricia RemónUwe Pischel
Methods in Enzymology
K Mosbach, B Mattiasson
Tijdschrift voor ziekenverpleging
M du Gardijn
© 2021 Meta ULC. All rights reserved