Reversible magnetic resonance imaging changes in a case of neuroleptic malignant syndrome

The American Journal of Emergency Medicine
Rajendra Singh JainShankar Tejwani

Abstract

Neuroleptic malignant syndrome (NMS) is a life-threatening neurologic emergency associated with the use of mainly typical antipsychotic drugs. It is characterized by fever, altered mental status, generalized rigidity, autonomic instability, myoclonus, raised creatine phosphokinase, rhabdomyolysis, and leukocytosis. Neuroimaging (brain computed tomography/magnetic resonance imaging [MRI]) is usually normal in most of the cases of NMS. Magnetic resonance imaging findings have not been well elucidated in NMS as yet. Very few cases have been reported worldwide. We herein, report a case of a 42-year-old patient of NMS, who presented to us with reversible changes in MRI brain. This case report highlights the possible MRI changes in NMS and their plausible mechanism.

References

Jan 1, 1992·Journal of Neural Transmission. General Section·T BeckerH Beckmann
Oct 1, 2009·Biomedical Imaging and Intervention Journal·Sa Al-EdrusS Muda
Jan 1, 2011·The Neurohospitalist·Brian D Berman

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Citations

Sep 22, 2015·The American Journal of Emergency Medicine·Shah SweniPonniah Thirumalaikolundusubramanian

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