Reversible peripheral neuropathy induced by vitamin B12 deficiency

Neurophysiologie clinique = Clinical neurophysiology
G SaklyM Dogui

Abstract

To describe an electroclinical presentation of a peripheral neuropathy in a patient who suffered from vitamin B12 deficiency. We report the case of a 56-year-old man who, 17 years after a subtotal gastrectomy, presented with a diffuse sensory-motor demyelinating peripheral neuropathy with multifocal alteration of conduction confirmed by electromyography. Its causal relationship with vitamin B12 deficiency was biologically demonstrated. This neuropathy improved within a few days after intramuscular hydroxocobalamin treatment. Both clinical and electrophysiological signs had totally disappeared 3 months later on. This observation demonstrates that, in spite of its poor outcome reported by several authors, peripheral neuropathy induced by vitamin B12 deficiency can recover completely with substitutive treatment.

References

Jan 1, 1986·Journal of the Neurological Sciences·R DeaconI Chanarin
Sep 1, 1980·Archives of Neurology·K S KosikA J Cretella
Aug 5, 1998·Neuroradiology·K YamadaY Numaguchi
Dec 17, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·B HemmerC H Lücking
Apr 5, 2002·Current Treatment Options in Neurology·David S. Saperstein, Richard J. Barohn
Dec 6, 2003·Clinical Chemistry and Laboratory Medicine : CCLM·Giuseppe ScalabrinoElena Mutti

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

Related Papers

Neurophysiologie clinique = Clinical neurophysiology
J M Pardal-FernándezJ Marco-Giner
Epilepsy Research
Christian M Korff, Douglas R Nordli
Journal of Neurology, Neurosurgery, and Psychiatry
Roberto MichelucciCarlo Alberto Tassinari
© 2021 Meta ULC. All rights reserved