Reversible renal failure due to the use of captopril in a renal allograft recipient treated with cyclosporin

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
T AhmadE J Eastham

Abstract

Angiotensin-converting enzyme (ACE) inhibitors are widely used for the treatment of hypertension, but caution is advised because these drugs may induce reversible acute renal failure. Although this has been ascribed in some cases to nephrotoxicity, hypotension, a hypersensitivity reaction, and interstitial nephritis, most cases have been associated with stenosis of the renal arteries or arterioles occurring in either native or transplanted kidneys. We describe a case of reversible acute renal failure due to the use of captopril in a renal allograft recipient who had no evidence of any of these conditions, but who was also receiving cyclosporin therapy.

Citations

Dec 26, 2001·Current Opinion in Nephrology and Hypertension·Giuseppe Remuzzi, Norberto Perico
Jan 30, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ludwig Patzer
Feb 14, 2003·Current Opinion in Urology·Leszek TylickiWalter H Hörl
May 29, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Matthias LorenzMartin Haas
May 29, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Bertram L KasiskeJon J Snyder
Jan 13, 2011·Advances in Chronic Kidney Disease·Mario F Rubin

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