Review: Application of Nanoparticles in Urothelial Cancer of the Urinary Bladder

Journal of medical and biological engineering
Chieh-Hsiao ChenJia-Jin Chen

Abstract

Bladder cancer is a common malignancy of the urinary tract, which generally develops in the epithelial lining of the urinary bladder. The specific course of treatment depends on the stage of bladder cancer; however, therapeutic strategies typically involve intravesical drug delivery to reduce toxicity and increase therapeutic effects. Recently, metallic, polymeric, lipid, and protein nanoparticles have been introduced to aid in the treatment of bladder cancer. Nanoparticles are also commonly used as pharmaceutical carriers to improve interactions between drugs and the urothelium. In this review, we classify the characteristics of bladder cancer and discuss the types of nanoparticles used in various treatment modalities. Finally we summarize the potential applications and benefits of various nanoparticles in intravesical therapy.

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Dec 22, 2015·The Journal of Urology·Lori Birder
Mar 8, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Kuan Yin HsiaoShyh Ming Kuo
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Jun 3, 2021·Cancers·Mahmood BaraniSadanand Pandey

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