PMID: 11328251May 1, 2001Paper

Review article: current endoscopic therapeutic options in the management of variceal bleeding

Alimentary Pharmacology & Therapeutics
A Helmy, P C Hayes

Abstract

Variceal bleeding is a frequent and life-threatening complication of portal hypertension. The first episode of variceal bleeding is not only associated with a high mortality, but also with a high recurrence rate in those who survive. Therefore, many studies and randomized clinical trials have focused on different therapeutic strategies aiming to prevent the first episode of variceal bleeding (primary prophylaxis), to control haemorrhage during the acute bleeding episode (emergency treatment), and to prevent re-bleeding (secondary prophylaxis). These strategies involve pharmacological, endoscopic, surgical, and interventional radiological modalities. This review concentrates on the clinical aspects of the endoscopic modalities used to treat oesophageal variceal haemorrhage, including variceal injection sclerotherapy, variceal band ligation, and the use of tissue adhesives (glue) and their substitutes. We also draw conclusions from the available literature regarding the use of endoscopic modalities in primary prophylaxis, emergency treatment, and secondary prophylaxis of variceal re-bleeding. The management of gastric varices and variceal bleeding during pregnancy is also addressed.

References

Sep 1, 1992·Baillière's Clinical Gastroenterology·S K Sarin, D Lahoti
Dec 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S K SarinU K Makwana
Jun 4, 1992·The New England Journal of Medicine·G V StiegmannS R Lowenstein
May 1, 1992·Endoscopy·S M MühldorferC Ell
May 1, 1992·Endoscopy·J Baillie, P Yudelman
Jul 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S DasarathyK Ramachandran
Nov 1, 1991·Journal of Hepatology·A E GimsonR Williams
Jun 20, 1991·The New England Journal of Medicine·UNKNOWN Veterans Affairs Cooperative Variceal Sclerotherapy Group
Mar 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D WestabyR Williams
Dec 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T AndreaniR Poupon
Apr 1, 1990·The British Journal of Surgery·S K MathurR Ramakantan
May 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J LimmerH G Beger
Feb 1, 1989·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D WestabyR Williams
May 1, 1986·Digestive Diseases and Sciences·G D'AmicoE Marubini
Sep 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G L BumgardnerD E Sutherland
Aug 1, 1988·The British Journal of Surgery·S KitanoK Sugimachi
Mar 1, 1988·Gastrointestinal Endoscopy·G Van Stiegmann, J S Goff
Oct 13, 1988·The New England Journal of Medicine·UNKNOWN North Italian Endoscopic Club for the Study and Treatment of Esophageal Varices
Mar 1, 1988·The British Journal of Surgery·S W Hosking, A G Johnson
Jun 1, 1986·Gastrointestinal Endoscopy·G Van StiegmannJ H Sun
Aug 1, 1986·Gastrointestinal Endoscopy·W Trudeau, T Prindiville
Jan 24, 1986·JAMA : the Journal of the American Medical Association·A W LarsonJ Weiner
Sep 1, 1986·Digestive Diseases and Sciences·R Williams, D Westaby
Jul 1, 1986·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D WestabyR Williams
Mar 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·W E FleigH Ditschuneit
Jul 1, 1986·The British Journal of Surgery·S KitanoP C Bornman
May 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G Garcia-TsaoM Glickman
Jan 1, 1986·Digestive Diseases and Sciences·S L WeissH R Gould
Aug 1, 1973·The British Journal of Surgery·R N PughR Williams
Apr 1, 1969·Annals of Internal Medicine·R H ResnickE T O'Hara

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Citations

Mar 17, 2005·Current Treatment Options in Gastroenterology·Aric J Hui, Joseph J Y Sung
Feb 19, 2005·Journal of Clinical Gastroenterology·Hubert H Nietsch
Jan 16, 2010·BMC Gastroenterology·Florian PetraschAlbrecht Hoffmeister
Jul 21, 2012·World Journal of Gastrointestinal Endoscopy·Joaquin Poza CordonJose Manuel Suárez de Parga
Sep 6, 2014·Current Gastroenterology Reports·Dana CrisanAlina Tantau
Sep 17, 2013·World Journal of Gastroenterology : WJG·Dae-Seong MyungYoung-Eun Joo
Jun 6, 2012·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·K ChaudhuriA Biswas
Jan 10, 2016·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·UNKNOWN Italian Association for the Study of the Liver (AISF), UNKNOWN Italian Association for the Study of the Liver AISF
Mar 19, 2008·Best Practice & Research. Clinical Gastroenterology·Càndid VillanuevaCarlos Guarner
Aug 5, 2003·Alimentary Pharmacology & Therapeutics·J W FergusonP C Hayes
Jun 10, 2006·Liver International : Official Journal of the International Association for the Study of the Liver·Ahmed HelmyPeter C Hayes
Jul 21, 2005·The American Journal of Emergency Medicine·Siang-Hiong GohShu-Woan Lee
Sep 17, 2015·Endoscopic Ultrasound·Payal Saxena, Sundeep Lakhtakia
Nov 5, 2014·Journal of Hepato-biliary-pancreatic Sciences·Kenneth F BinmoellerSteven D Kane
Oct 4, 2014·World Journal of Gastroenterology : WJG·Christos Triantos, Maria Kalafateli
Oct 8, 2014·Journal of Viral Hepatitis·A LicataP L Almasio
Jul 19, 2018·World Journal of Gastroenterology : WJG·Ioanna AggeletopoulouChristos Triantos
Oct 8, 2020·Clinical Endoscopy·Dominic A StaudenmannPayal Saxena
Mar 13, 2021·Drugs·Saleh A Alqahtani, Sunguk Jang
Jan 30, 2008·Gastrointestinal Endoscopy·Walter G ParkGeorge Triadafilopoulos

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