PMID: 11929384Apr 4, 2002Paper

Review article: faecal markers in the assessment of activity in inflammatory bowel disease

Alimentary Pharmacology & Therapeutics
Andrew PoullisMichael A Mendall

Abstract

The fundamental pathological process behind ulcerative colitis and Crohn's disease is intestinal inflammation. As the precise cause of this is not yet completely understood, current treatment strategies are aimed at reducing or eliminating the inflammation. Endoscopic examination and histological analysis of biopsy specimens remain the 'gold standard' methods for detecting and quantifying bowel inflammation; however, these techniques are costly, invasive, and repeated examinations are unpopular with patients. Disease activity questionnaires and laboratory 'inflammatory markers', although widely used, show an unreliable correlation with endoscopy and histology. New markers need to be developed to detect and quantify bowel inflammation. These would be of use diagnostically and also an aid to pharmacological treatment.

References

Jan 1, 1978·Scandinavian Journal of Gastroenterology·J Powell-TuckJ E Lennard-Jones
Sep 1, 1992·Scandinavian Journal of Gastroenterology·A G RøsethH Schjønsby
Apr 1, 1992·European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies·N KapelJ G Gobert
Jan 1, 1992·Scandinavian Journal of Gastroenterology·E O Adeyemi, H J Hodgson
Apr 1, 1990·Scandinavian Journal of Gastroenterology·S NordgrenL Hultén
Jan 1, 1990·The Medical Clinics of North America·T M Bayless, M L Harris
Nov 1, 1989·Digestive Diseases and Sciences·W E Roediger
Apr 1, 1983·Gut·S H SaverymuttuV S Chadwick
Mar 1, 1994·Scandinavian Journal of Gastroenterology·H HoveP B Mortensen
Jul 1, 1996·Scandinavian Journal of Gastroenterology·L M HandyA Ferguson
Jun 1, 1997·Molecular Pathology : MP·B JohneI Dale
Jul 21, 1998·Scandinavian Journal of Gastroenterology·T SaikiK Tanikawa
Oct 29, 2000·The American Journal of Gastroenterology·P J LimburgA R Zinsmeister
Oct 29, 1955·British Medical Journal·S C TRUELOVE, L J WITTS

❮ Previous
Next ❯

Citations

Apr 14, 2009·Inflammatory Bowel Diseases·Javier P GisbertFernando Gomollon
Mar 18, 2009·Inflammatory Bowel Diseases·Javier P GisbertJosé Maté
Jul 17, 2008·International Journal of Colorectal Disease·A Damms, S C Bischoff
Oct 18, 2003·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·F CostaG Maltinti
Nov 3, 2005·Nature Clinical Practice. Gastroenterology & Hepatology·Jon O LundbergArne G Roseth
Aug 2, 2007·Annals of Surgery·Debra SudanAlan Langnas
Feb 18, 2012·Clinical and Vaccine Immunology : CVI·Hermie J M HarmsenGerard Dijkstra
Sep 14, 2007·BMC Microbiology·Wendy RodenburgIngeborg M J Bovee-Oudenhoven
Sep 3, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Frank HellerTimm H Westhoff
Jun 29, 2012·Digestive Diseases and Sciences·Anna VaiopoulouGeorge Zografos
Aug 28, 2013·Nutrition & Diabetes·S HawkesworthA M Prentice
Mar 1, 2008·Journal of Crohn's & Colitis·E F StangeUNKNOWN European Crohn's and Colitis Organisation (ECCO)
Nov 26, 2015·Scandinavian Journal of Gastroenterology·Rocio Ferreiro-IglesiasJuan Enrique Dominguez-Muñoz
Aug 16, 2005·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·M B OleksiewiczT G Klenø
Feb 22, 2016·Journal of Gastroenterology·Shapur IkhtaireWaliul Islam Khan
Jan 28, 2014·Journal of Medical Microbiology·Simon J WhiteheadRousseau Gama
Jul 8, 2008·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·J P Gisbert, A G McNicholl
Nov 25, 2011·Annals of Clinical Biochemistry·Ruth M Ayling
Mar 21, 2007·Clinica Chimica Acta; International Journal of Clinical Chemistry·Imerio AngrimanMario Plebani
Oct 30, 2004·Scandinavian Journal of Gastroenterology·M B Oleksiewicz
Jul 7, 2007·Scandinavian Journal of Gastroenterology·Massimo MontaltoGiovanni Gasbarrini
Jun 12, 2014·Inflammatory Bowel Diseases·Emily K WrightMichael A Kamm
Aug 30, 2017·Expert Review of Gastroenterology & Hepatology·Gerard CumminsSandy Cochran
Jan 13, 2011·The American Journal of Gastroenterology·Jessica R BiesiekierskiPeter R Gibson
Nov 15, 2006·The American Journal of Gastroenterology·Massimo MontaltoGiovanni Gasbarrini
Nov 23, 2012·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Soo Jung ParkWon Ho Kim
Apr 7, 2007·Journal of Pediatric Gastroenterology and Nutrition·Thomas R WalkerPaul A Rufo
Aug 24, 2018·Journal of Crohn's & Colitis·Christian MaaserUNKNOWN European Crohn’s and Colitis Organisation [ECCO] and the European Society of Gastrointestinal and Abdominal Radiology [ESGAR
Sep 8, 2010·Journal of Pediatric Gastroenterology and Nutrition·Nathalie KapelChristophe Dupont
Jul 26, 2013·The Journal of Veterinary Medical Science·Erika NakashimaEiki Takahashi
May 9, 2012·Journal of Clinical Gastroenterology·Anna LicataAntonio Craxì
Apr 19, 2003·European Journal of Gastroenterology & Hepatology·Andrew PoullisKeith Wiener
Nov 30, 2018·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Ashish Kumar JhaRavish Ranjan
Mar 1, 2003·European Journal of Gastroenterology & Hepatology·Livia BianconeFrancesco Pallone
Mar 10, 2017·Expert Review of Gastroenterology & Hepatology·Paula Ministro, Diana Martins
Jan 11, 2017·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Juan María Vázquez MorónCarlos Ruiz Frutos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.