The threat of bacterial colonization and biofilm formation poses the most important limitation on the use and development of prosthetic devices in human medicine. Data from the literature suggest that microbial adherence effected by the glycocalyx is a fundamental factor in sepsis involving biomaterials and that it may explain the resistance of such infections to host defense mechanisms and to antibiotherapy. A full appreciation of the existence and the consequences of the biofilm mode of bacterial growth is required so that we can both prevent and eliminate these protected microbial reservoirs.
Microbial colonization of indwelling central venous catheters: statistical evaluation of potential contaminating factors
In vitro study of the possible role of the intrauterine contraceptive device tail in ascending infection of the genital tract
Physiological function of descending noradrenaline projections to the spinal cord: role in post-decapitation convulsions
Tobramycin resistance of Pseudomonas aeruginosa cells growing as a biofilm on urinary catheter material.
Microbial colonization of tailed and tailless intrauterine contraceptive devices: influence of the mode of insertion in the rabbit
Culture of the surfaces of urinary catheters to sample urethral flora and study the effect of antimicrobial therapy.
Toxicity of metal particles in tissue culture. I. A new assay method using cell counts in the phase of replication
Examination of the morphology of bacteria adhering to peritoneal dialysis catheters by scanning and transmission electron microscopy.
Experimental foreign body infections in mice challenged with slime-producing Staphylococcus epidermidis.
Effects of physical configuration and chemical structure of suture materials on bacterial adhesion. A possible link to wound infection
Adherence of bacteria to pediatric intravenous catheters and needles and its relation to phlebitis in animals
Scanning and transmission electron microscopy of in situ bacterial colonization of intravenous and intraarterial catheters.
Colonization of bacteria on polyvinyl chloride and Teflon intravascular catheters in hospitalized patients.
Quantitative adherence in vitro of coagulase-negative staphylococci to intravascular catheters: inhibition with D-mannosamine
Production of mucoid microcolonies by Pseudomonas aeruginosa within infected lungs in cystic fibrosis.
A technique to study the bacterial colonization of surfaces employing chemotaxis chambers and scanning electron microscopy
A scanning and transmission electron microscopic study of the surfaces of intrauterine contraceptive devices
A Pseudomonas fluorescens type 6 secretion system is related to mucoidy, motility and bacterial competition
Biofilm formation by the oral pioneer colonizer Streptococcus gordonii: an experimental and numerical study
The physical properties of biogels and their permeability for macromolecular drugs and colloidal drug carriers
The diagnostic performance of the beta-glucan assay in the detection of intra-amniotic infection with Candida species
In vitro response of Escherichia coli to antibiotics and ultrasound at various insonation intensities
Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.
Biofilm & Infectious Disease
Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.