Review: Microbial colonization of prosthetic devices

Microbial Ecology
M JacquesJ W Costerton


The threat of bacterial colonization and biofilm formation poses the most important limitation on the use and development of prosthetic devices in human medicine. Data from the literature suggest that microbial adherence effected by the glycocalyx is a fundamental factor in sepsis involving biomaterials and that it may explain the resistance of such infections to host defense mechanisms and to antibiotherapy. A full appreciation of the existence and the consequences of the biofilm mode of bacterial growth is required so that we can both prevent and eliminate these protected microbial reservoirs.


Jun 9, 1977·The New England Journal of Medicine·D G MakiH W Sarafin
Mar 1, 1976·Journal of Biomedical Materials Research·A G GristinaJ F Nicastro
Jun 1, 1985·American Journal of Surgery·W SamsoondarC Oxley
Apr 1, 1985·Antimicrobial Agents and Chemotherapy·J C NickelJ W Costerton
Apr 1, 1985·European Journal of Clinical Microbiology·J C NickelJ W Costerton
Apr 1, 1985·Journal of Medical Microbiology·J S CheesbroughR G Finch
May 24, 1985·Science·A G GristinaC D Hobgood
Apr 1, 1968·The Journal of Bone and Joint Surgery. American Volume·A M Pappas, J Cohen
Jul 1, 1969·Journal of Clinical Pathology·R Holt
Mar 1, 1983·Applied and Environmental Microbiology·T J Marrie, J W Costerton
Jul 1, 1982·Infection and Immunity·G D ChristensenE H Beachey
May 23, 1980·Science·L L Hench
Mar 1, 1983·The Journal of Surgical Research·N K ShethP G Sohnle
Jun 1, 1983·Archives of Internal Medicine·T J Marrie, J W Costerton
Nov 1, 1981·Archives of Surgery·W S MooreK Keown
Jun 1, 1984·Journal of Clinical Microbiology·T J Marrie, J W Costerton
Sep 1, 1984·Journal of Clinical Microbiology·T R FransonP G Sohnle
Oct 1, 1984·The Journal of Infectious Diseases·P VaudauxU E Nydegger
Sep 1, 1983·Journal of General Microbiology·A H HogtJ Feijen
Apr 1, 1984·Journal of Biomedical Materials Research·R E BaierJ M Carter
Jul 1, 1981·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·M S KarlanE P Goldberg
Mar 1, 1983·The Journal of Infectious Diseases·D RotrosenJ E Edwards
Jun 15, 1983·American Journal of Obstetrics and Gynecology·T J Marrie, J W Costerton
Jun 1, 1980·The Journal of Infectious Diseases·D J CleriS J Seligman
May 1, 1981·Canadian Journal of Microbiology·K J ChengJ W Costerton
Jan 1, 1981·Annual Review of Microbiology·J W CostertonK J Cheng
Feb 1, 1982·Urological Research·B Sugarman
Feb 1, 1982·Journal of Clinical Microbiology·E S LeakeM J Wright
Oct 1, 1982·The Journal of Infectious Diseases·G PetersG Pulverer
Oct 1, 1982·The Journal of Infectious Diseases·W ZimmerliU E Nydegger
Nov 1, 1980·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·M S KarlanE P Goldberg

❮ Previous
Next ❯


Jul 1, 1991·Journal of Biomedical Materials Research·A BuretJ W Costerton
Jan 1, 1993·Journal of Gastroenterology and Hepatology·J Y SungJ W Costerton
Dec 22, 1998·Journal of Biomaterials Science. Polymer Edition·L L JohnsonW G Pitt
Feb 26, 2015·Frontiers in Cellular and Infection Microbiology·Carla Renata ArciolaLucio Montanaro
Dec 12, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Percy PacoraSonia S Hassan
Jul 1, 1997·Journal of Biomaterials Applications·R G Williams, W G Pitt
Mar 6, 2021·ACS Biomaterials Science & Engineering·Zhen GuoYi Zhang
Nov 1, 1994·Antimicrobial Agents and Chemotherapy·W G PittR D Sagers
Feb 1, 1994·Applied and Environmental Microbiology·O M VäisänenM S Salkinoja-Salonen

❮ Previous
Next ❯

Related Concepts

Related Feeds


Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.