Review of Clinical Outcome Assessments in Pediatric Attention-Deficit/Hyperactivity Disorder

Neuropsychiatric Disease and Treatment
Jessica T MarkowitzSharon B Wigal

Abstract

Various clinical outcome assessments (COAs) are used in clinical research to assess and monitor treatment efficacy in pediatric attention-deficit/hyperactivity disorder (ADHD) trials. It is unclear whether the concepts assessed are those that are important to patients and their caregivers. The concepts measured by commonly used COAs in this population have not been explicitly compared. We conducted reviews of the qualitative literature to extract information on pediatric ADHD-related concepts reported by pediatric patients, parents, and teachers. Using these concepts, we developed a conceptual framework of pediatric ADHD using both the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria and the additional symptoms and behavioral impacts identified in the literature. We searched for COAs that have been used in pediatric ADHD research and mapped their items based on their conceptual underpinning. Of the 27 COAs found in the empirical literature, 4 COAs assessed only DSM symptoms. The most comprehensive coverage of our conceptual framework was seen in the Swanson, Nolan, and Pelham Rating Scale-DSM-IV (SNAP-IV). Eighteen COAs were used in at least 1 clinical trial: ADHD-Rating Scale-IV (ADHD-RS-IV) was used most o...Continue Reading

References

Jun 20, 1998·Journal of Abnormal Child Psychology·M L WolraichT Y Pinnock
Jul 15, 2006·Journal of Attention Disorders·Sharon B Wigal, Timothy L Wigal
Feb 27, 2009·Journal of the American Academy of Child and Adolescent Psychiatry·Joan M Daughton, Christopher J Kratochvil
Oct 18, 2011·Pediatrics·UNKNOWN Subcommittee on Attention-Deficit/Hyperactivity DisorderSusanna Visser
Apr 25, 2012·Culture, Medicine and Psychiatry·Ligia ChavezGlorisa Canino
Mar 20, 2014·Neuropsychiatry·Jeffery N Epstein, Richard E A Loren
Aug 30, 2014·Academic Pediatrics·Donna WoodsRamesh Sachdeva
Sep 28, 2015·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Marc K WaltonUNKNOWN International Society for Pharmacoeconomics and Outcomes Research Task Force for Clinical Outcomes Assessment
Dec 5, 2015·Frontiers in Psychiatry·Alaa M HamedHanna E Stevens
Dec 15, 2015·JBI Database of Systematic Reviews and Implementation Reports·Britt Laugesen, Mette Groenkjaer
Feb 22, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Trevor ThompsonMargaret Weiss
Oct 5, 2017·Journal of Child and Adolescent Mental Health·Meisie Mofokeng, Anna E van der Wath
Jan 27, 2019·Paediatrics & Child Health·Mark E FeldmanStacey A Bélanger

❮ Previous
Next ❯

Citations

Jun 7, 2021·Developmental Medicine and Child Neurology·Gabriel M RonenDavid L Streiner
Jun 21, 2021·Revista colombiana de psiquiatría·Alejandra María Gómez-ÁlzateJuan David Palacio-Ortiz

❮ Previous
Next ❯

Software Mentioned

DPREMB

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.