Review of ionic models of vagal-cardiac pacemaker control

Journal of Theoretical Biology
S DokosB G Celler

Abstract

Mathematical models of ion currents in pacemaker cells of the heart and their associated modulation by vagal stimulation have provided numerous insights into the ionic mechanisms underlying parasympathetic control of heart rate. In this article, ionic models described in the literature are reviewed and compared, with a view to examining their effectiveness in reproducing known chronotropic responses to vagal stimulation.

Citations

Sep 19, 2001·Australasian Physical & Engineering Sciences in Medicine·A R BathN H Lovell

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