Abstract
Those patients with perianal Crohn's disease or ulcerative colitis experience a difficult to treat disease process with a delayed state and often inability to heal despite current therapies. The approaches currently used to treat these patients with corticosteroids, antibiotics, immunomodulators, anti-tumor necrosis factor-α drug, and surgical repair are limited in their healing ability. This review presents all current literature since emergence in the early 2000s of stem cell therapy for patients with perianal inflammatory bowel disease and analyzes the efficacy, outcomes and safety within these studies.
References
May 21, 2003·International Journal of Colorectal Disease·Damian García-OlmoLuis García-Sancho
Dec 9, 2003·The Journal of Gene Medicine·Alain ChapelDominique Thierry
Oct 30, 2004·Blood·Shaul BeythJacob Rachmilewitz
Feb 5, 2005·Blood·Xiao-Xia JiangNing Mao
Jun 4, 2005·Diseases of the Colon and Rectum·Damián García-OlmoJosé Antonio Rodríguez-Montes
Mar 11, 2009·Diseases of the Colon and Rectum·Damian Garcia-OlmoMaria Pascual
Apr 29, 2009·Blood·Grazia Maria SpaggiariLorenzo Moretta
Jan 25, 2011·Gut·Rachele CiccocioppoGino Roberto Corazza
Sep 26, 2012·Cell Transplantation·Yong Beom ChoChang Sik Yu
Jan 26, 2013·Haematologica·Sara M MeliefHelene Roelofs
Feb 14, 2013·Stem Cells·Woo Yong LeeChang Sik Yu
May 29, 2013·Stem Cells·Sara M MeliefHelene Roelofs
Sep 6, 2013·Haematologica·Sara M MeliefHelene Roelofs
Apr 2, 2015·Stem Cells Translational Medicine·Yong Beom ChoChang Sik Yu
Jun 28, 2015·Gastroenterology·Ilse MolendijkDaniel W Hommes
Apr 13, 2017·Gastroenterology·Allan B DietzWilliam A Faubion
Dec 27, 2017·Gastroenterology·Julián PanésUNKNOWN ADMIRE CD Study Group Collaborators
Citations
Sep 8, 2020·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Paschalis NtoliosArgyrios Tzouvelekis
Feb 23, 2020·Biochemistry. Biokhimii︠a︡·N V BobkovaG T Sukhikh
Apr 27, 2019·Expert Review of Gastroenterology & Hepatology·Nicole LopezWillam J Sandborn
Jun 23, 2021·Advanced Drug Delivery Reviews·Olga HartwigClaus-Michael Lehr
Jul 10, 2021·World Journal of Gastroenterology : WJG·Oliver Schwandner