Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease

World Journal of Transplantation
Francis E DaileyVeysel Tahan

Abstract

Those patients with perianal Crohn's disease or ulcerative colitis experience a difficult to treat disease process with a delayed state and often inability to heal despite current therapies. The approaches currently used to treat these patients with corticosteroids, antibiotics, immunomodulators, anti-tumor necrosis factor-α drug, and surgical repair are limited in their healing ability. This review presents all current literature since emergence in the early 2000s of stem cell therapy for patients with perianal inflammatory bowel disease and analyzes the efficacy, outcomes and safety within these studies.

References

May 21, 2003·International Journal of Colorectal Disease·Damian García-OlmoLuis García-Sancho
Jun 4, 2005·Diseases of the Colon and Rectum·Damián García-OlmoJosé Antonio Rodríguez-Montes
Mar 11, 2009·Diseases of the Colon and Rectum·Damian Garcia-OlmoMaria Pascual
Apr 2, 2015·Stem Cells Translational Medicine·Yong Beom ChoChang Sik Yu
Dec 27, 2017·Gastroenterology·Julián PanésUNKNOWN ADMIRE CD Study Group Collaborators

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Citations

Sep 8, 2020·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Paschalis NtoliosArgyrios Tzouvelekis
Feb 23, 2020·Biochemistry. Biokhimii︠a︡·N V BobkovaG T Sukhikh
Apr 27, 2019·Expert Review of Gastroenterology & Hepatology·Nicole LopezWillam J Sandborn
Jul 10, 2021·World Journal of Gastroenterology : WJG·Oliver Schwandner

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