Review of Temephos Discriminating Concentration for Monitoring the Susceptibility of Anopheles labranchiae (Falleroni, 1926), Malaria Vector in Morocco.

Malaria Research and Treatment
C FarajF Chandre

Abstract

In Morocco, the resistance monitoring of Anopheles labranchiae larvae to temephos is done using discriminating concentration of 0.125 mg, which is half of the WHO recommended dose for Anopheles. However, this dosage seemed to be too high to allow an early detection of the resistance and its revision was found necessary. The present study was carried out during May-June 2008 and 2009 in nine provinces from the north-west of the country. The aim was to determine the lethal concentrations LC100 of temephos for the most susceptible populations and to define the discriminating dosage as the double of this value. The bioassays were conducted according to WHO standard operating protocol to establish the dose-mortality relationship and deduct the LC50 and LC95. The results of this study indicated that the LC100 obtained on the most susceptible populations was close to 0.05 mg/L. Therefore, the temephos discriminating dosage for susceptibility monitoring of An. labranchiae larvae in Morocco was set to be 0.1 mg/L.

References

Aug 14, 2010·Malaria Journal·Céline TotyDidier Fontenille

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Citations

Apr 11, 2015·Genetics Research International·Vinaya ShettyN J Shetty
Apr 22, 2015·The American Journal of Tropical Medicine and Hygiene·Mirza LalaniToby Leslie
Nov 6, 2014·The American Journal of Tropical Medicine and Hygiene·Shirly GrynbergEli Schwartz
Feb 11, 2015·The American Journal of Tropical Medicine and Hygiene·Corey M PeakMaciej F Boni
Nov 8, 2013·The American Journal of Tropical Medicine and Hygiene·Mark PurdyDavid Rublin
Aug 5, 2010·The American Journal of Tropical Medicine and Hygiene·Alessandro BartoloniFrancesco Castelli
May 6, 2015·The American Journal of Tropical Medicine and Hygiene·Silvie HuijbenAndrew F Read
Dec 2, 2010·The American Journal of Tropical Medicine and Hygiene·M Irene MasanjaPeter D McElroy
Jul 31, 2013·The American Journal of Tropical Medicine and Hygiene·Juan Gabriel PiñerosSilvia Blair
Oct 21, 2015·The American Journal of Tropical Medicine and Hygiene·Fiorella Llanos-CheaAlejandro Llanos-Cuentas

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