Review of the clinical results of fast neutron therapy

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
G Schmitt, A Wambersie

Abstract

The clinical results reported from the different neutron therapy centres are reviewed. Fast neutrons were shown to be useful in the treatment of locally extended inoperable salivary gland tumours (average local control rates 67% for neutrons compared to 28% for photons). For paranasal sinuses and some tumours of the head and neck area, especially extended tumours with large fixed lymph nodes, neutrons could also be of interest. By contrast, the results obtained for brain tumours were, in general, disappointing. Neutrons were shown to be beneficial in the treatment of well differentiated soft tissue sarcomas, as well as to bone- and chondrosarcomas. For locally extended prostatic adenocarcinoma, a RTOG randomized trial gave local control rates of 77% for mixed schedule compared to 31% for photons. Neutrons could be useful also for palliative treatment of melanomas. Further studies are needed in order to evaluate the benefit of fast neutrons for other localizations such as uterine cervix, bladder and rectum. It can be concluded that fast neutrons could be of interest for about 10% of the radiotherapy patients, but it is likely that the new high-energy hospital-based cyclotrons will further extend the indications of neutron therap...Continue Reading

References

Aug 1, 1976·AJR. American Journal of Roentgenology·R G ParkerC M Shaw
Aug 1, 1989·American Journal of Clinical Oncology·G E LaramoreL W Davis
Nov 1, 1988·International Journal of Radiation Oncology, Biology, Physics·T W GriffinM H Maor
Sep 1, 1987·International Journal of Radiation Oncology, Biology, Physics·M Catterall, R D Errington
Jun 1, 1988·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·B R GriffinJ Eenmaa
May 1, 1986·International Journal of Radiation Oncology, Biology, Physics·A BorthneH Vermund
Mar 1, 1980·International Journal of Radiation Oncology, Biology, Physics·M CatterallB Chaucer
Sep 1, 1983·International Journal of Radiation Oncology, Biology, Physics·T W GriffinA Rodriguez-Antunez
Dec 1, 1984·Cancer·M P RichterR L Goodman
Aug 1, 1984·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J S AbbatucciA Busson
Aug 1, 1981·International Journal of Radiation Oncology, Biology, Physics·J J Battermann, K Breur
Dec 1, 1982·International Journal of Radiation Oncology, Biology, Physics·W DuncanG R Kerr
Jul 1, 1981·International Journal of Radiation Oncology, Biology, Physics·M Abe, M Takahashi

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Citations

Mar 29, 2001·Journal of Surgical Oncology·D Turns
Mar 1, 1995·Radiation and Environmental Biophysics·J M CossetJ L Habrand
Apr 15, 2004·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Gefei ZhouZuhong Xu
May 18, 2004·Surgical Oncology·K Harish
Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·J P SlabbertL Bohm
Mar 17, 1999·International Journal of Radiation Oncology, Biology, Physics·R G Dale, B Jones
Apr 6, 2006·Palliative & Supportive Care·Steven D PassikRobert Sprang
Jun 1, 1997·Cancer Nursing·S M Mahon, D M Casperson
Feb 8, 2013·Medical Physics·Jay BurmeisterMichael Snyder
May 15, 1998·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·S SchallaE W Hahn
Jul 8, 1999·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·F J ProttN Willich
Aug 1, 1992·The British Journal of Radiology·D J HusbandH M Warenius
Jan 1, 1994·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·H M WareniusJ H Peacock
Dec 3, 2009·Phytotherapy Research : PTR·Ming ZhouYunqing Cai
Jan 1, 1994·Acta Oncologica·J Denekamp
Jan 3, 2001·Journal of Advanced Nursing·K Herth
Sep 6, 2003·Journal of Advanced Nursing·Hung-Ru Lin, Susan M Bauer-Wu
Oct 28, 2016·Oncotarget·Clayton A SmithMichael L Freeman
Jun 1, 1991·International Journal of Radiation Biology·M Spotheim-MaurizotM Charlier
Apr 1, 1997·Physics in Medicine and Biology·G WolberW Maier-Borst
Mar 15, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J Del RoweB Fisher
Jan 24, 2015·American Journal of Clinical Oncology·Shilpen A PatelGeorge E Laramore

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