Review of the literature: severe hyperphosphatemia

The American Journal of the Medical Sciences
L ThatteB A Roos


A patient with a markedly elevated serum phosphorus level (23.9 mg/dL) is described, followed by a brief review of severe hyperphosphatemia. Elevated serum phosphorus levels may be artifactual or true. True hyperphosphatemia is usefully subdivided according to (a) whether phosphorus is added to the extracellular fluid from a variety of exogenous or endogenous sources, or (b) whether the urinary excretion of phosphorus is reduced from either decreased glomerular filtration or increased tubular reabsorption. Severe hyperphosphatemia, defined herein as levels of 14 mg/dL or higher, is almost invariably multifactorial--usually resulting from addition of phosphorus to the extracellular fluid together with decreased phosphorus excretion. The hyperphosphatemia of the patient described herein appeared to result from a combination of dietary phosphorus supplementation, acute renal failure, acute pancreatitis, and ischemic bowel disease, complicated by lactic acidosis.


Nov 1, 1979·The American Journal of Medicine·R J WinterO C Green
Sep 29, 1977·The New England Journal of Medicine·L R O'ConnorJ E Bethune
May 19, 1979·British Medical Journal·A KanferF Chatelet
Jul 1, 1975·Clinical Science and Molecular Medicine·R J WaltonR Smith
Jul 1, 1976·Annals of Internal Medicine·A KofflerS G Massry
Feb 1, 1975·The Journal of Pediatrics·W L MillerF C Bartter
Nov 1, 1992·European Journal of Clinical Investigation·Y IlanP Lavie
Apr 1, 1992·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J A Delmez, E Slatopolsky
Jul 1, 1992·The American Journal of Emergency Medicine·G L Sternbach, J Varon
Jun 1, 1989·The Journal of Pediatrics·M P WilsonJ A Johnson
Apr 1, 1986·Journal of Clinical Gastroenterology·M M Berenson, R G Lee
Jan 1, 1988·Annual Review of Nutrition·Y N Berner, M Shike
Mar 1, 1986·Archives of Internal Medicine·J R WeisingerV Paz-Martínez
Jan 1, 1988·JPEN. Journal of Parenteral and Enteral Nutrition·W B VernonR D Stewart
Mar 1, 1988·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·S G AdlerJ D Kopple
Feb 1, 1988·Southern Medical Journal·J R OsterB J Materson
Nov 1, 1985·The American Journal of Medicine·R KeblerP Cadnapaphornchai
Apr 1, 1985·Archives of Internal Medicine·D J LeeheyR W Reid
Jun 1, 1985·The Journal of Clinical Endocrinology and Metabolism·K W LylesM K Drezner
Nov 1, 1985·The American Journal of Medicine·M Biberstein, B A Parker
Feb 1, 1971·Anesthesiology·R A Pollock, R L Watson
Dec 20, 1973·The New England Journal of Medicine·J ZusmanM E Nesbit
Mar 1, 1973·Annals of Surgery·D H Brooks, L C Carey
Jan 29, 1972·British Medical Journal·M G Betro, R W Pain
Jul 1, 1972·Metabolism: Clinical and Experimental·E W Reimold
Dec 1, 1971·The Journal of Clinical Investigation·S B HulleyS N Rosen
Sep 1, 1966·The American Journal of Medicine·G W Jordan
Aug 1, 1968·The Journal of Clinical Investigation·E SlatopolskyN S Bricker
Jul 1, 1966·Anesthesiology·J P Bunker
May 1, 1967·The Journal of Clinical Endocrinology and Metabolism·R I Breuer, J LeBauer
Dec 1, 1981·The Journal of Pediatrics·M A MikatiS S Najjar
Nov 1, 1981·Proceedings of the Society for Experimental Biology and Medicine·E C SmithM P Westerman
Aug 1, 1984·Canadian Journal of Physiology and Pharmacology·J R OsterC A Vaamonde
Jul 1, 1981·JPEN. Journal of Parenteral and Enteral Nutrition·S VanlandinghamS R Newmark
Aug 1, 1983·American Journal of Surgery·L D May, M M Berenson
Jun 1, 1982·The British Journal of Surgery·W G JamiesonD Durand
Dec 1, 1982·Canadian Journal of Physiology and Pharmacology·J R OsterC A Vaamonde

❮ Previous
Next ❯


Dec 14, 2002·The Journal of Emergency Medicine·Joseph R Shiber, Amal Mattu
May 20, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Andreas L BirkenfeldFriedrich C Luft
Dec 18, 2009·Pediatric Emergency Care·Simone Brasil de Oliveira IglesiasWerther Brunow de Carvalho
Mar 18, 2011·The American Journal of Emergency Medicine·Subramanian SenthilkumaranPonniah Thirumalaikolundusubramanian
Oct 16, 2007·Clinica Chimica Acta; International Journal of Clinical Chemistry·Jason W LaneThomas J Walsh
Aug 15, 2014·Environmental Geochemistry and Health·M W C Dharma-WardanaC R Panabokke
Mar 11, 2017·Journal of Complementary & Integrative Medicine·Suphamat Wanitsriphinyo, Mayuree Tangkiatkumjai
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Jeffrey A Kraut, Nicolaos E Madias
Apr 30, 2017·The American Journal of Case Reports·Seyed Ali Sadjadi, Alexander Pi
Dec 19, 2019·Journal of Clinical Medicine·Emilie ReberZeno Stanga
Jan 19, 1999·The American Journal of the Medical Sciences·J R OsterC F Vieira

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Epigenetics Insights from Twin Studies

Find the latest research on epigenetics and twin studies here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.