Review of the magnitude of folate and vitamin B12 deficiencies worldwide

Food and Nutrition Bulletin
Erin McLeanLindsay H Allen

Abstract

Human deficiencies of folate and vitamin B12 result in adverse effects which may be of public health significance, but the magnitude of these deficiencies is unknown. Therefore, we examine the prevalence data currently available, assess global coverage of surveys, determine the frequency with which vitamin status assessment methods are used, and identify patterns of status related to geographical distribution and human development. Surveys were identified through PubMed and the Vitamin and Mineral Nutrition Information System at the World Health Organization (WHO). Since different thresholds were frequently used to define deficiency, measures of central tendency were used to compare blood vitamin concentrations among countries. The percentage of countries with at least one survey is highest in the WHO Regions of South-East Asia and Europe. Folate and vitamin B12 status were most frequently assessed in women of reproductive age (34 countries), and in all adults (27 countries), respectively. Folate status assessment surveys assessed plasma or serum concentrations (55%), erythrocyte folate concentrations (21%), or both (23%). Homocysteine was assessed in one-third of the surveys of folate and vitamin B12 status (31% and 34% respec...Continue Reading

References

Oct 4, 1995·JAMA : the Journal of the American Medical Association·C J BousheyA G Motulsky
Jun 1, 1995·Journal of Internal Medicine·A K al-Momen
Oct 29, 2000·Annals of Nutrition & Metabolism·M Krajcovicová-KudláckováK Babinská
Jan 11, 2000·European Journal of Clinical Nutrition·M OlivaresD Wegner
Jun 30, 2001·The British Journal of Nutrition·J ArnaudJ Barnouin
Jul 14, 2001·The American Journal of Clinical Nutrition·S E VollsetP M Ueland
Aug 31, 2001·European Journal of Clinical Nutrition·M WartanowiczL Konopka
Dec 1, 2001·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·S Y HessR F Hurrell
Aug 2, 2002·Journal of Child Neurology·Kenton R HoldenUNKNOWN Honduran Neural Tube Defect Project Team
Oct 17, 2002·JAMA : the Journal of the American Medical Association·Lena GeorgeSven Cnattingius
Dec 20, 2002·Journal of Nutritional Science and Vitaminology·Hyeon-Sook Lim, Young-Ran Heo
Jan 28, 2003·European Journal of Clinical Nutrition·G AlfthanA Aro
Jun 7, 2003·European Journal of Clinical Nutrition·E PlanellsJ Llopis
Oct 2, 2003·The Journal of Nutrition·Eva HertrampfChristine Pfeiffer
Nov 11, 2003·The Journal of Nutrition·Xiang GaoKatherine L Tucker
Jun 11, 2004·Annual Review of Nutrition·Sally P Stabler, Robert H Allen
Jul 20, 2004·Birth Defects Research. Part A, Clinical and Molecular Teratology·Ronald G MungerFlorentino S Solon
Aug 21, 2004·Clinical Chemistry·Helga RefsumBengt F Kase
Sep 11, 2004·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·K SchulpisI Papassotiriou
Oct 16, 2004·European Journal of Clinical Nutrition·T J GreenS M Williams
Oct 23, 2004·International Journal of Cancer. Journal International Du Cancer·Johan HultdinPär Stattin
Dec 2, 2004·Indian Journal of Pediatrics·Priyali PathakPreeti Singh
Dec 30, 2004·The Journal of Nutrition·Andrew J CliffordGladys Block
Apr 23, 2005·American Journal of Medical Genetics. Part a·Jorge S López-CameloEduardo E Castilla

❮ Previous
Next ❯

Citations

Nov 12, 2009·Current Opinion in Clinical Nutrition and Metabolic Care·Patrick J Stover
Dec 28, 2011·Endocrine Journal·Mehmet ErdoganKulaksizoglu Mustafa
May 2, 2012·Nature Reviews. Gastroenterology & Hepatology·Marianne J NielsenSøren K Moestrup
Jan 6, 2017·Clinical and Translational Gastroenterology·Priscila SalaDan L Waitzberg
May 10, 2017·International Journal for Equity in Health·Sharea IjazJelena Savović
Jul 1, 2017·Nature Reviews. Disease Primers·Ralph GreenChittaranjan Yajnik
Aug 3, 2017·Birth Defects Research·Sutapa Bandyopadhyay NeogiVenkata Satyanarayana Murthy Gudlavalleti
Nov 16, 2017·Annals of the New York Academy of Sciences·Lynn B Bailey, Dorothy B Hausman
Aug 29, 2018·Journal of Alzheimer's Disease : JAD·Jared M CampbellEdoardo Aromataris
May 10, 2019·Frontiers in Nutrition·Caterina TinelliMarco Feligioni
May 17, 2019·Advances in Nutrition·Eva F G NaninckElske M Brouwer-Brolsma
Jul 16, 2010·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Sarah G ObicanAnthony R Scialli
Dec 25, 2010·Cadernos de saúde pública·Lana Carneiro Almeida, Marly Augusto Cardoso
Nov 17, 2011·International Journal of Laboratory Hematology·C RischL Risch
Jul 15, 2009·The British Journal of Nutrition·Garden TabacchiLluís Serra-Majem
Dec 6, 2012·Molecular Nutrition & Food Research·Evelyne M van Uitert, Régine P M Steegers-Theunissen
Oct 4, 2013·Pediatric Hematology and Oncology·Yasemin Işık BalcıKazım Küçüktaşcı
Feb 3, 2016·BMC Pregnancy and Childbirth·Robinson Ramírez-VélezFelipe Lobelo
Jun 29, 2016·Critical Reviews in Food Science and Nutrition·Fabien SaubadeChristèle Humblot
Jul 1, 2015·Food and Nutrition Bulletin·Alex BritoLindsay H Allen
Apr 13, 2017·European Journal of Clinical Nutrition·J L FinkelsteinC Duggan
Mar 17, 2019·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Perla Meneses-SanchezM Elba Gonzalez-Mejia
Dec 19, 2019·The Cochrane Database of Systematic Reviews·Jai K DasZulfiqar A Bhutta
Jan 1, 2020·Journal of Diabetes and Metabolic Disorders·S SurendranKarani Santhanakrishnan Vimaleswaran
Aug 20, 2008·Food and Nutrition Bulletin·Lindsay H Allen
Jul 16, 2010·Food and Nutrition Bulletin·Lindsay H AllenGilbert S Omenn
Jun 10, 2010·Nature Biotechnology·Hans De SteurJacques Viaene
Jul 16, 2010·Food and Nutrition Bulletin·Robert J BerryUNKNOWN Folic Acid Working Group
Oct 10, 2015·The Journal of Nutrition·Lynn B BaileyDaniel J Raiten
Aug 21, 2013·Human Reproduction Update·Régine P M Steegers-TheunissenKevin D Sinclair
Sep 22, 2018·Annals of the New York Academy of Sciences·Lisa M RogersLynn B Bailey

❮ Previous
Next ❯

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