Review of the role of progesterone in the management of postnatal mood disorders

Journal of Psychosomatic Obstetrics and Gynaecology
A C Granger, M R Underwood

Abstract

Postnatal mood disorders (maternity blues, postnatal depression and puerperal psychosis) are cross-cultural symptoms that are commonly seen in primary care by general practitioners and midwives, by gynecologists and obstetricians, and within the psychiatric services. One of several hypotheses for their causation is falling progesterone levels in the postpartum period. Progesterone supplements are therefore currently used in the treatment of postnatal mood disorders, both in primary and secondary health care settings. The evidence for this is reviewed. The MEDLINE and PSYCHLIT databases from 1966 to 1999 were searched. References reporting observational data on progesterone levels around delivery or therapeutic studies using progesterone were retrieved. Additional references were identified by citation tracking from these and direct contact with available authors. Eight papers were identified. Although there is some weak evidence for its role in maternity blues and some theoretical justification for its use, there is no robust primary research to support the use of progesterone in the treatment of postnatal mood disorders. Progesterone is being used to prevent recurrence of postnatal depression but the evidence supporting its ef...Continue Reading

References

Mar 1, 1975·Anesthesiology·L Gyermek, L F Soyka
Apr 1, 1979·The British Journal of Psychiatry : the Journal of Mental Science·S A Montgomery, M Asberg
Apr 1, 1976·The British Journal of Psychiatry : the Journal of Mental Science·P N NottM G Gelder
Sep 1, 1991·Archives of General Psychiatry·M W O'HaraE J Wright
Nov 1, 1988·American Journal of Obstetrics and Gynecology·E S ArafatR N Andersen
Jun 1, 1987·The British Journal of Psychiatry : the Journal of Mental Science·J L CoxR Sagovsky
May 1, 1986·The British Journal of Psychiatry : the Journal of Mental Science·P R GardG Waldron
May 1, 1967·International Journal of Neuropharmacology·L GyermekN Fleming
Apr 1, 1973·The British Journal of Psychiatry : the Journal of Mental Science·B Pitt
Jun 1, 1971·The British Journal of Psychiatry : the Journal of Mental Science·K Dalton
Jan 1, 1968·Archives of General Psychiatry·I D YalomD A Hamburg
Feb 1, 1983·Journal of Affective Disorders·P M Helms, R E Smith
Jun 1, 1984·Journal of Affective Disorders·A FeksiR G Newcombe
Jul 1, 1983·Clinical Endocrinology·V KueviJ C Wise
Feb 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·J L CoxR E Kendell
Apr 1, 1980·The British Journal of Psychiatry : the Journal of Mental Science·E S PaykelE S Rassaby
Jan 1, 1980·Journal of Psychosomatic Research·G S Stein
Nov 1, 1994·Social Psychiatry and Psychiatric Epidemiology·R Kumar
Nov 1, 1994·Addiction·H Pétursson
Apr 9, 1994·BMJ : British Medical Journal·B HarrisD Riad-Fahmy
Nov 1, 1996·The British Journal of Psychiatry : the Journal of Mental Science·D B Pritchard, B Harris
Jan 26, 1956·The New England Journal of Medicine·W H BOWER, M D ALTSCHULE
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
Apr 1, 1965·Psychological Reports·M ZUCKERMAN, B LUBIN

❮ Previous
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Citations

Jan 1, 2016·The Journal of Steroid Biochemistry and Molecular Biology·Wei GaoTobias Stalder
Sep 21, 2007·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Nicole LetourneauJanet Stoppard
Jul 27, 2010·Contraception·Rita Tsai, Jonathan Schaffir
Oct 20, 2006·Journal of Psychiatric Research·Claudia M KlierMaria Zeller
Apr 27, 2017·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Rebecca StonerPierre Schembri-Wismayer
Jun 24, 2004·International Journal of Technology Assessment in Health Care·Judith LumleyCreina Mitchell
Jan 2, 2004·Journal of Psychosomatic Obstetrics and Gynaecology·S Gale, B L Harlow
Feb 10, 2004·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Lei YaoM Saeed Dhamee
Sep 15, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Milan RudicNeven Zarkovic
Apr 11, 2008·Neuroscience and Behavioral Physiology·A G KoshchavtsevV V Lorer
Jul 20, 2019·Therapeutic Advances in Psychopharmacology·Alexandre González-Rodríguez, Mary V Seeman
Jun 18, 2002·The Medical Journal of Australia·Anthony F JormBryan Rodgers
Jul 30, 2020·Best Practice & Research. Clinical Obstetrics & Gynaecology·Lindsay R StandevenLauren M Osborne

❮ Previous
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