Review: the use of proteomics as a research methodology for studying cancer-related fatigue: a review.

Palliative Medicine
Ollie Minton, Patrick Stone

Abstract

There is an increasing emphasis on using translational research to examine mechanisms and increase our understanding of disease. Translational research involves the use of basic science techniques to generate new treatments for use in a clinical setting - the so called 'bench to bedside' approach. This methodology could be used to enhance our understanding of complex symptoms such as cancer-related fatigue. This review will examine specifically the potential role of the science of protein structure and function (proteomics) as a technique to improve our knowledge in this area. This will include an explanation of the specific methods used in this research in order to increase our understanding of the mechanisms of cancer-related fatigue and discuss potential directions for future research with the development of more targeted therapies.

References

Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Jan 1, 1993·Journal of Psychosomatic Research·T ChalderE P Wallace
Feb 22, 1996·Nature·P TodorovM Tisdale
Apr 3, 1999·British Journal of Cancer·P StoneR A'Hern
Feb 16, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J E BowerT R Belin
Oct 13, 2001·International Journal of Radiation Oncology, Biology, Physics·H GeinitzM Molls
Dec 12, 2001·Journal of Pain and Symptom Management·P StoneJ Hardy
Jul 26, 2002·Psychosomatic Medicine·Julienne E BowerJohn L Fahey
Apr 20, 2004·International Journal of Radiation Oncology, Biology, Physics·Christopher WrattenJ W Denham
Mar 10, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Tyvin RichFrancis Lévi
Feb 8, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·G PrueF Cramp
Apr 20, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J Paul MonkMiguel A Villalona-Calero
Nov 14, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Ana Villar-GareaAxel Imhof
Dec 19, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Mi-Ryung Kim, Chan-Wha Kim
Dec 21, 2006·Brain, Behavior, and Immunity·Christian SchubertJoel E Dimsdale
Dec 8, 2007·Breast Cancer Research and Treatment·O Minton, P Stone
Apr 22, 2008·The Cochrane Database of Systematic Reviews·F Cramp, J Daniel
Jun 11, 2008·Palliative Medicine·F SkorpenS Kaasa
Aug 6, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·O Minton, P Stone
Oct 11, 2008·Nature Reviews. Cancer·Bostjan SerugaIan F Tannock
Jan 23, 2009·The Cochrane Database of Systematic Reviews·Martine Margaretha GoedendorpGijs Bleijenberg
Jun 24, 2009·The Pharmacogenomics Journal·H Landmark-HøyvikV Dumeaux
Feb 17, 2010·Database : the Journal of Biological Databases and Curation·Maria C CostanzoUNKNOWN the Saccharomyces Genome Database Project
Jan 1, 2009·Database : the Journal of Biological Databases and Curation·Olivier ArnaizJean Cohen

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Citations

Jul 10, 2003·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Emma ReamIrena Anna Frei
May 25, 2013·Cancer·Ollie MintonPatrick C Stone
Jul 29, 2015·EJC Supplements : EJC : Official Journal of EORTC, European Organization for Research and Treatment of Cancer ... [et Al.]·Neil K AaronsonLonneke V van de Poll-Franse
Jan 8, 2011·Acta Biochimica Et Biophysica Sinica·Feng GeXian'en Zhang
Jul 3, 2018·Journal of Sleep Research·Philipp O ValkoChristian R Baumann
Apr 25, 2020·International Journal of Molecular Sciences·Yong Qin KohAlexandre Chan

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