Revised and extended serum cotinine cut-offs to classify smokers and non-smokers

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
Ram B Jain

Abstract

To revise and extend the previously published serum cotinine cut offs to classify smokers and non-smokers for US adolescents and adults. Cross-sectional data (N = 10171) from National Health and Nutrition Examination Survey for 2011-2014 were used to compute serum cotinine cut-offs to classify smokers and non-smokers for US adults aged ≥20 years and 2007-2014 (N = 4583) data were used to compute serum cotinine cut-offs for US adolescents aged 12-19 years. Specificities and sensitivities for the cut-offs among adults were ≥95% and ≥75% among adolescents. For adults, serum cotinine cut-offs in ng/mL to classify smokers from non-smokers were 3.3 for the total population, 4.13 for males, 2.99 for females, 4.03 for non-Hispanic whites, 8.85 for non-Hispanic blacks, 0.377 for Mexican Americans, 1.72 for other Hispanics and 1.41 for non-Hispanic Asians. For adolescents, serum cotinine cut-offs in ng/mL to classify smokers from non-smokers were 0.765 for the total population, 1.1 for males, 0.408 for females, 1.2 for non-Hispanic whites, 1.98 for non-Hispanic blacks, 0.215 for Mexican Americans and 0.321 for other Hispanics. Serum cotinine cut-offs to distinguish smokers from non-smokers for US adults and adolescents were developed.

References

Feb 6, 2016·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Ram B Jain
Dec 17, 2016·International Journal of Environmental Research and Public Health·Sungroul Kim
Jan 4, 2017·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Ram B Jain

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Citations

Nov 7, 2019·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Ram B Jain
Aug 7, 2019·Biomarkers in Medicine·Erin L TompkinsSheryl A Bedno
Jun 25, 2020·Environmental Science and Pollution Research International·Ram B Jain
Oct 18, 2020·Environmental Science and Pollution Research International·Ram B Jain
Jan 14, 2021·Environmental Science and Pollution Research International·Ram B Jain
Apr 12, 2021·Environmental Science and Pollution Research International·Ram B Jain

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