Revised Modified Response Evaluation Criteria in Solid Tumors for Assessment of Response in Malignant Pleural Mesothelioma (Version 1.1)

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer
Samuel G Armato, Anna Nowak

Abstract

Malignant pleural mesothelioma poses unique difficulties in tumor measurement and response assessment; however, robust and reproducible assessment of response is critically important in the conduct, interpretation, and reporting of clinical trials. The current de facto standard for the assessment of mesothelioma tumor response, "modified RECIST" (Response Evaluation Criteria in Solid Tumors), was published in 2004 as a research paper. Practical application of the modified RECIST guidelines has suffered from varied interpretations, resulting in inaccuracies and inconsistencies in tumor response assessment across and within mesothelioma clinical trials. The presented "modified RECIST 1.1 for mesothelioma" response assessment guidelines provide a much-needed update that incorporates recommendations from RECIST 1.1 and approaches to other practical issues, including: (1) definition of minimally measurable disease; (2) definition of measurable lesions; (3) acceptable measurement location; (4) non-pleural disease considerations; (5) characterization of non-measurable pleural disease; (6) assessment of pathological lymph nodes; (7) establishing progressive disease; and (8) accommodations for bilateral pleural disease. These modified R...Continue Reading

Citations

May 26, 2020·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Isabelle OpitzGiuseppe Cardillo
May 3, 2019·Expert Opinion on Biological Therapy·Anna K NowakAlistair Cook
May 27, 2020·The European Respiratory Journal·Arnaud ScherpereelPaul Martin Putora
Nov 10, 2018·F1000Research·Lawek Berzenji, Paul Van Schil
Aug 17, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Theresa A Gelzinis
Feb 5, 2021·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·E NadalJ de Castro-Carpeño
Jun 5, 2021·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Maria J DisselhorstPaul Baas
May 18, 2021·Seminars in Nuclear Medicine·Egesta LopciLioe-Fee de Geus-Oei

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