Revisiting the cytotoxicity of quantum dots: an in-depth overview

Biophysics Reviews
Sohrab NikazarMuhammad Salman Shanavas

Abstract

Recently, medical research has been shifting its focus to nanomedicine and nanotherapeutics in the pursuit of drug development research. Quantum dots (QDs) are a critical class of nanomaterials due to their unique properties, which include optical, electronic, and engineered biocompatibility in physiological environments. These properties have made QDs an attractive biomedical resource such that they have found application as both in vitro labeling and in vivo theranostic (therapy-diagnostic) agents. Considerable research has been conducted exploring the suitability of QDs in theranostic applications, but the cytotoxicity of QDs remains an obstacle. Several types of QDs have been investigated over the past decades, which may be suitable for use in biomedical applications if the barrier of cytotoxicity can be resolved. This review attempts to report and analyze the cytotoxicity of the major QDs along with relevant related aspects.

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Citations

Jun 6, 2020·Biophysics Reviews·Damien Hall
Jul 22, 2020·Journal of Fluorescence·Faezeh AskariJohn F Trant
Jan 28, 2021·International Journal of Molecular Sciences·Katarzyna Dominika KaniaŁukasz Pułaski
Nov 4, 2020·International Journal of Molecular Sciences·Łukasz JanusDariusz Bogdał
Apr 4, 2021·International Journal of Molecular Sciences·Seyedeh Maryam HosseinikhahMagali Cucchiarini
May 6, 2021·International Journal of Molecular Sciences·Yung-Li WangHui-Wen Chiu
Jul 1, 2021·ACS Sustainable Chemistry & Engineering·Agnieszka M Jastrzębska, Alexey S Vasilchenko

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Methods Mentioned

BETA
irradiates
biosensors
X-ray

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