Revitalising Silver Nitrate for Caries Management

International Journal of Environmental Research and Public Health
Sherry Shiqian GaoChun Hung Chu

Abstract

Silver nitrate has been adopted for medical use as a disinfectant for eye disease and burned wounds. In dentistry, it is an active ingredient of Howe's solution used to prevent and arrest dental caries. While medical use of silver nitrate as a disinfectant became subsidiary with the discovery of antibiotics, its use in caries treatment also diminished with the use of fluoride in caries prevention. Since then, fluoride agents, particularly sodium fluoride, have gained popularity in caries prevention. However, caries is an infection caused by cariogenic bacteria, which demineralise enamel and dentine. Caries can progress and cause pulpal infection, but its progression can be halted through remineralisation. Sodium fluoride promotes remineralisation and silver nitrate has a profound antimicrobial effect. Hence, silver nitrate solution has been reintroduced for use with sodium fluoride varnish to arrest caries as a medical model strategy of caries management. Although the treatment permanently stains caries lesions black, this treatment protocol is simple, painless, non-invasive, and low-cost. It is well accepted by many clinicians and patients and therefore appears to be a promising strategy for caries control, particularly for yo...Continue Reading

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Citations

Apr 26, 2018·International Journal of Molecular Sciences·Ollie Yiru YuChun-Hung Chu
May 30, 2020·International Journal of Environmental Research and Public Health·Stefano CianettiGuido Lombardo
Sep 1, 2020·Journal of Dental Research·K J ChenC H Chu
Aug 29, 2020·Bioinorganic Chemistry and Applications·Claudia Butrón Téllez GirónFacundo Ruiz
Apr 2, 2019·JDR Clinical and Translational Research·S S GaoC H Chu
Aug 16, 2019·Pharmaceutical Research·Anastasiia B ShatanDaniel Horák
Jan 21, 2021·International Journal of Molecular Sciences·Paweł KowalczykIda Franiak-Pietryga
Mar 4, 2021·International Dental Journal·Gemma BridgeMarta Lomazzi
Mar 12, 2021·European Journal of Dentistry·Magdalena Stawarz-JaneczekJolanta Pytko-Polończyk

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Methods Mentioned

BETA
X-ray
sedation

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