RF shimming for spectroscopic localization in the human brain at 7 T.

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
H P HetheringtonJullie W Pan

Abstract

Spectroscopic imaging of the human head at short echo times (<or=15 ms) typically requires suppression of signals from extracerebral tissues. However, at 7 T, decreasing efficiency in B1+ generation (hertz/watt) and increasing spectral bandwidth result in dramatic increases in power deposition and increased chemical shift registration artifacts for conventional gradient-based in-plane localization. In this work, we describe a novel method using radiofrequency shimming and an eight-element transceiver array to generate a B1+ field distribution that excites a ring about the periphery of the head and leaves central brain regions largely unaffected. We have used this novel B1+ distribution to provide in-plane outer volume suppression (>98% suppression of extracerebral lipids) without the use of gradients. This novel B1+ distribution is used in conjunction with a double inversion recovery method to provide suppression of extracerebral resonances with T1s greater than 400 ms, while having negligible effect on metabolite ratios of cerebral resonances with T1s>1000 ms. Despite the use of two adiabatic pulses, the high efficiency of the ring distribution allows radiofrequency power deposition to be limited to 3-4 W for a pulse repetitio...Continue Reading

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Citations

Mar 29, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Mustapha BouhraraRichard G Spencer
Jul 22, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J W PanH P Hetherington
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Nov 20, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jullie W PanHoby P Hetherington
Nov 20, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Chathura KumaragamageRobin A de Graaf
May 4, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Sebastian SchmitterPierre-François Van de Moortele
Mar 12, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Roman FleysherDaniel Sodickson
Aug 7, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Hoby P HetheringtonJullie W Pan
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Jan 4, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jullie W PanHoby P Hetherington
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Apr 17, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J W PanH P Hetherington
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