RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder

Neuroscience Letters
Kaija HuuhkaEsa Leinonen

Abstract

We studied the association between RGS4 (rs951436) polymorphism and treatment response in electroconvulsive therapy (ECT) as well as risk of treatment-resistant depression. The study sample consisted of 119 patients with major depressive disorder (MDD) and 384 healthy control subjects. RGS4 polymorphism was not associated with treatment response in ECT or risk of MDD. According to the present data, the impact of RGS4 genotype is not decisive in major depressive disorder. The results provide preliminary data on the impact of RGS4 polymorphism in treatment response in ECT.

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Citations

May 11, 2010·International Clinical Psychopharmacology·Magali NoroIsabelle Massat
Dec 3, 2014·European Journal of Pharmacology·Barbara J CaldaroneSarah L King
Jun 27, 2015·Pharmacogenomics·Hooman MirzakhaniHenk-Jan Guchelaar
May 27, 2016·Expert Review of Neurotherapeutics·Amene SaghazadehNima Rezaei
Oct 30, 2016·Neuroscience Letters·Martina PinnaGian Paolo Minnai
May 26, 2017·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Emanuel Schwarz
Apr 12, 2016·Human Psychopharmacology·Janine J Benson-MartinKatharina Domschke

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