Rhabdomyoblastic differentiation in a leiomyosarcoma of the retroperitoneum

Human Pathology
F Roncaroli, V Eusebi

Abstract

A case of leiomyosarcoma of the retroperitoneum with rhabdomyoblastic areas which developed in a 59-year-old woman is reported. The tumor was composed mostly of spindle cells immunoreactive with desmin and smooth muscle actin antisera. In the lesion there were no fewer than five patches constituted by large pleomorphic elements which reacted with antidesmin, sarcomeric actin and myoglobin antisera. These dual features were interpreted as the result of a divergent differentiation of neoplastic cells.

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Citations

Apr 16, 2004·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Masayuki Shintaku, Kentarou Sekiyama
Oct 18, 2000·Pathology Oncology Research : POR·E SzékelyP Kaliszky
Jun 2, 2009·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Monika VermaW Glenn McCluggage
Jul 18, 2001·Pathology Oncology Research : POR·E SzékelyL Nagy
Oct 18, 2005·Virchows Archiv : an International Journal of Pathology·Florian GrabellusKurt Werner Schmid
Feb 19, 2000·The American Journal of Surgical Pathology·V EusebiJ Rosai
Jun 9, 2016·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Luca RoncatiAntonio Maiorana

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