PMID: 16509464Mar 3, 2006Paper

Rhabdomyolysis and acute renal failure following arthroscopic knee surgery in a college football player taking creatine supplements

Clinical Nephrology
N P ShethJ S Berns

Abstract

We describe a college football player and weight-lifter who unexpectedly developed rhabdomyolysis and nonoliguric acute renal failure (ARF) following arthroscopic knee surgery. There was swelling and pain without evidence of a compartment syndrome postoperatively. The patient reported that he was an avid weight-lifter and that he was taking up to 10 g/d of a creatine supplement during the 6 weeks prior to this surgery. His ARF resolved over several days, with a peak serum creatinine of 2.3 mg/dl and peak creatine kinase (CK) of 194,000 U/l, following administration of intravenous fluids, mannitol, and sodium bicarbonate. Given the rarity of clinically significant rhabdomyolysis with this type of operation, we suggest that the patient's use of creatine increased the risk of skeletal muscle injury due to ischemia from intra-operative tourniquet application.

Citations

Apr 18, 2008·Pediatric Emergency Care·Raemma Paredes Luck, Sandi Verbin
Mar 3, 2011·Journal of the International Society of Sports Nutrition·Frederico Sc FrancoAntônio J Natali
Apr 3, 2012·Neuroscience and Biobehavioral Reviews·Patricia J Allen
Aug 29, 2007·Pediatric Clinics of North America·Anthony LattavoPeter D Rogers
Jan 29, 2010·Clinical Pharmacology and Therapeutics·C A Haller
Jan 22, 2008·Clinics in Sports Medicine·Paola BrancaccioFrancesco Mario Limongelli
Mar 10, 2009·The Journal of Hand Surgery, European Volume·P A StoreyF D Burke
Apr 20, 2011·European Journal of Anaesthesiology·Jean-Pierre EstebePhilippe Richebe
Jan 14, 2009·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Sarah Dehoney, Marlea Wellein
Mar 3, 2010·The Korean Journal of Internal Medicine·Yong Gu LeeDong Ho Yang
Sep 1, 2007·European Journal of Anaesthesiology·M A BroomM R Parris
Sep 21, 2019·Acta orthopaedica et traumatologica turcica·Hisahiro TonotsukaKeishi Marumo
Mar 24, 2017·Sports Medicine·Eric S RawsonMark A Tarnopolsky

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