Rhabdomyolysis following recent severe coxsackie virus infection in patient with chronic renal failure: one case report and a review of the literature

Renal Failure
Yi-Mei WangZhi-Bin Ye

Abstract

Coxsackie virus infection may be life-threatening, although in most cases, it is asymptomatic. Coxsackie virus infection can cause rhabdomyolysis. This study reports a 39-year-old female patient with chronic renal failure who presented with fever, myalgia, anuria, edema, vomiting, diarrhea, exacerbation of renal function, elevation of serum CK, CK-MB, CK-MM, myoglobin, and liver function abnormality. Serology for Coxsackie virus IgM antibody was positive at first, and IgG antibody became positive 4 weeks later. Muscle biopsy showed skeletal muscle denaturalization and necrosis. She underwent hemodialysis three times per week and then kidney transplantation. No evidence suggests relapse of Coxsackie virus infection 5 months after transplantation. As illustrated with the present case, serological testing may reveal an early, quick, and simple diagnosis in a case of rhabdomyolysis after a viral illness.

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Citations

Oct 29, 2014·The American Journal of Tropical Medicine and Hygiene·Shi-Yu HuangLin Wang
Apr 18, 2008·Pediatric Emergency Care·Raemma Paredes Luck, Sandi Verbin
Apr 7, 2009·The Korean Journal of Hepatology·Soe Hee AnnYoung Sok Lee
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May 29, 2010·Neurology India·Burak GündüzHalil Toplamaoğlu
Sep 25, 2014·Transplant Infectious Disease : an Official Journal of the Transplantation Society·H-Y JungC-D Kim

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