Rheumatic manifestations of hepatitis C virus chronic infection: Indications for a correct diagnosis

World Journal of Gastroenterology : WJG
Carlo PalazziIgnazio Olivieri

Abstract

Hepatitis C virus (HCV) is a hepato- and lymphotropic agent that is able to induce several autoimmune rheumatic disorders: vasculitis, sicca syndrome, arthralgias/arthritis and fibromyalgia. The severity of clinical manifestations is variable and sometimes life-threatening. HCV infection can mimic many primitive rheumatic diseases, therefore, it is mandatory to distinguish HCV-related manifestations from primitive ones because the prognosis and therapeutic strategies can be fairly dissimilar. The new direct-acting antivirals drugs can help to avoid the well-known risks of worsening or new onset of autoimmune diseases during the traditional interferon-based therapies.

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Citations

Jun 21, 2017·International Journal of Molecular Sciences·Isabela SiloşiCristian Adrian Siloşi
Sep 21, 2017·The New England Journal of Medicine·Lee ParkSarah E Turbett
Jun 21, 2018·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Luz Marina NavartaNelson Acosta-Rivero
Dec 5, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·Ídila Mont'Alverne Xavier de Oliveira, Rita do Socorro Uchôa da Silva
Apr 28, 2021·Mucosal Immunology·Evgeniya V Shmeleva, Francesco Colucci

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