Rheumatoid arthritis, anti-tumour necrosis factor treatment, and risk of squamous cell and basal cell skin cancer: cohort study based on nationwide prospectively recorded data from Sweden

BMJ : British Medical Journal
Pauline RaaschouARTIS study group

Abstract

To investigate the risk of squamous cell and basal cell skin cancer in patients with rheumatoid arthritis naive to biologic drugs, in patients starting tumour necrosis factor (TNF) inhibitor treatment, and in the general population. Population based cohort study. Nationwide data from Sweden. Cohort of patients with rheumatoid arthritis naive to biologics (n=46 409), cohort of patients with rheumatoid arthritis starting TNF inhibitor treatment as first biologic in 1998-2012 (n=12 558), and matched general population comparator cohort, identified through national quality of care and health registers. Hazard ratio of first in situ or invasive squamous cell skin cancer (1998-2012) and first basal cell cancer (2004-12). For basal cell cancer, the hazard ratio was 1.22 (95% confidence interval 1.07 to 1.41) comparing biologics-naive rheumatoid arthritis patients with the general population and 1.14 (0.98 to 1.33; 236 v 1587 events) comparing TNF inhibitor treated patients with biologics-naive patients. For squamous cell cancer, the hazard ratio was 1.88 (1.74 to 2.03) comparing biologics-naive rheumatoid arthritis patients with the general population and 1.30 (1.10 to 1.55; 191 v 847 events) comparing TNF inhibitors with biologics-na...Continue Reading

Citations

Nov 29, 2016·Rheumatic Diseases Clinics of North America·Padmapriya Sivaraman, Stanley B Cohen
Feb 6, 2017·Thérapie·François GueyffierUNKNOWN participants of Giens XXXII Round Table No. 2
Feb 7, 2017·Thérapie·François GueyffierUNKNOWN les participants à la table ronde n(o) 2 de Giens XXXII
Jun 9, 2017·Expert Opinion on Biological Therapy·Priyanka Vashisht, James O'dell
Jun 20, 2018·Pharmacoepidemiology and Drug Safety·Yesim OzgulerHasan Yazici
Jun 14, 2018·The British Journal of Dermatology·J Mazereeuw-HautierV Oji
Jan 30, 2018·Scandinavian Journal of Rheumatology·Jef DiernaesH F Lorentzen
Jan 31, 2019·Expert Review of Pharmacoeconomics & Outcomes Research·Patricia Vella BonannoBrian Godman
Feb 28, 2019·International Journal of Rheumatic Diseases·Chak Sing LauSwan Sim Yeap
Jul 10, 2018·Rheumatology·Clément LahayeMartin Soubrier
May 30, 2019·American Journal of Epidemiology·Kuo-An ChuJames Cheng-Chung Wei
Nov 7, 2019·Applied Health Economics and Health Policy·Caridad PontesBrian Godman
Dec 21, 2017·American Journal of Clinical Dermatology·Shamir GellerMeenal Kheterpal
Jul 3, 2020·Annals of the Rheumatic Diseases·Anja Strangfeld, Gerd R Burmester
Dec 3, 2016·Arthritis Research & Therapy·Jenny HumphreysDeborah Symmons
Jun 6, 2017·The British Journal of Dermatology·G Jones
Oct 6, 2018·Rheumatology·Roberto CaporaliCarlomaurizio Montecucco
Apr 30, 2020·Journal of Clinical Medicine·Maria Antonietta BarbieriEdoardo Spina
Aug 1, 2020·PharmacoEconomics·Carolina Zampirolli DiasAugusto Afonso Guerra-Junior
Mar 17, 2020·International Journal of Epidemiology·Ming-Li ChenJames Cheng-Chung Wei
May 22, 2018·Journal of the American Academy of Dermatology·Michael C CameronAnthony M Rossi
Feb 5, 2021·Journal of Clinical Medicine·Peter C TaylorJanet Pope
Jan 27, 2021·Stroke; a Journal of Cerebral Circulation·Kuan-Ying LiRenin Chang
Mar 28, 2021·Joint, Bone, Spine : Revue Du Rhumatisme·Joanna KedraRaphaèle Seror
Nov 30, 2020·Journal of the American Academy of Dermatology·Jonas A AdalsteinssonJon Gunnlaugur Jonasson
Jul 24, 2021·Frontiers in Medicine·Chun-Hui WeiJames Cheng-Chung Wei
Oct 6, 2021·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·T P VoigtA Tsianakas
Aug 25, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Monica E D'ArcyEric A Engels

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Carcinoma, Basal Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Bowen's Disease

Bowen's disease is thought of as an easily-treatable early stage of skin cancer, characterized by red, scaly patches on the skin. Discover the latest research on Bowen's disease here.