Rheumatoid arthritis: follow-up and response to treatment

European Journal of Radiology
A GiovagnoniF Amici

Abstract

To assess the role of diagnostic imaging techniques in the identification and follow-up of the anatomical damage induced by the chronic inflammatory process of rheumatoid arthritis (RA) not only to study the natural history of the disease but also and especially to assess the long-term response to disease-modifying anti-rheumatic drugs (DMARD). The relative literature data were reviewed and compared with our personal experience with different imaging modalities such as conventional radiography (CR), ultrasound (US) and magnetic resonance imaging (MRI). Several radiologic techniques have been used over the years to study articular damage in RA: they describe and quantify the articular damage (semi-quantitative analysis) based on a series of parameters and elementary anatomical lesions which are given a rising score. For its sensitivity in detecting early disease signs and the possibility to express anatomical damage progression quantitatively, Sharp's index is considered the best tool for evaluating RA patients. The close correlation between clinical parameters and the radiologic scores obtained regardless of the method applied led to a new concept of anatomical damage related to the 'radiologic progression of the disease' which...Continue Reading

References

Mar 1, 1992·Arthritis and Rheumatism·H E PaulusJ P Edmonds
Dec 30, 1983·The American Journal of Medicine·H K Genant
Nov 1, 1995·Arthritis and Rheumatism·K GaffneyS Blades
Dec 1, 1957·Annals of the Rheumatic Diseases·J H KELLGREN, J S LAWRENCE
Jun 25, 1949·Journal of the American Medical Association·O STEINBROCKERR C BATTERMAN

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Citations

Jun 18, 2003·Annals of the Rheumatic Diseases·P A Ory
Jan 10, 2006·Current Problems in Diagnostic Radiology·James Teh
Apr 28, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Fengying DaiXin Zhang
Oct 18, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jianghong CaiYinghuai Zhu

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