Rheumatoid arthritis with systemic necrotizing arteritis

Acta Pathologica Japonica
F KoizumiK Wakaki

Abstract

An autopsy case of rheumatoid arthritis with active polyarthritis, systemic necrotizing arteritis, pleuritis, pericarditis, rheumatoid nodules in a few organs and a healing gastric ulcer was reported. Histologically, systemic necrotizing arteritis was characterized by vascular changes of the following three types: Granulomatous arteritis with a characteristic arrangement of mesenchymal cells forming a palisade around coagulation necrosis of media and some of them formed a rheumatoid nodule-like lesion in the wall (RA type); Fibrinoid arteritis very similar to the Kussmaul-Maier type periarteritis nodosa (PN type); and chronic arteritis with endarterial proliferation (Ep type). Although it is hard to distinguish arteritis of PN type from the Kussmaul-Maier type periarteritis nodosa, arteritis of RA type with rheumatoid nodule-like lesion in the wall may be interpreted as an extremely developed form of vasculitis in rheumatoid arthritis.

References

Feb 1, 1954·The American Journal of Medicine·M BEVANSC RAGAN
Jun 1, 1957·Journal of Chronic Diseases·L SOKOLOFF, J J BUNIM
Jan 1, 1961·The American Journal of Medicine·F R SCHMIDC McEWEN
Jul 9, 1960·Canadian Medical Association Journal·A AronoffS Dworkin

Citations

Nov 1, 1980·Acta Pathologica Japonica·M FukaseK Wakaki

Related Concepts

Arteries
Arteritis
Rheumatoid Arthritis
Necrosis
Polyarteritis Nodosa

Related Feeds

Central Nervous System Vasculitis

Central nervous system vasculitis is a newly recognized inflammatory brain disease, which may develop as a primary condition, or secondary to an underlying systemic disease. Here is the latest research.