Rheumatologist perspective of the Brazilian consensus for detection of auto antibodies in HEp-2 CELLS.

Advances in Rheumatology
Isadora Carvalho Medeiros FrancescantonioWilson de Melo Cruvinel

Abstract

To evaluate the perception of rheumatologists regarding the recommendations of the Brazilian Consensus for detection of Autoantibodies (BCA) on HEp-2 Cells by Indirect Immunofluorescence assay (IFA) and how BCA recommendations help in clinical practice. A structured questionnaire regarding the BCA recommendations for detection and interpretations of autoantibodies in HEp-2 cells was applied to randomly selected rheumatologists. The results were tabulated using the Microsoft® Excel program, expressed as a simple percentage and the dichotomous data were analyzed using the Chi-square test and the Epi Info® program. Four hundred fuorteen rheumatologists participated in the study: 70% of them considered their knowledge of the HEp-2 IFA test satisfactory or excellent, and 43% said they knew the BCA recommendations in general, without distinguishing the edition of the BCA to which they refer. The Revista Brasileira de Rheumatologia/Advances in Rheumatology was the means of dissemination most consulted by specialists (50%). According to the rheumatologists' opinion, the most relevant pattern was the homogeneous nuclear (78%) and 65% stated they were satisfied with the BCA recommendations at a level of satisfaction greater than or equal...Continue Reading

References

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Dec 13, 2018·Methods in Molecular Biology·Alessandra Dellavance, Luis Eduardo Coelho Andrade
Jul 5, 2019·Advances in Rheumatology·Wilson de Melo CruvinelPaulo Luiz Carvalho Francescantonio
Jul 7, 2020·Clinical Chemistry and Laboratory Medicine : CCLM·Mônica Simon PradoLuis Eduardo Coelho Andrade

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