Abstract
Asthma and rhinitis often co-occur, and this potentially increases the disease severity and impacts negatively on the quality of life. We studied disease severity, airway responsiveness, atopy, quality of life and treatment in subjects with both asthma and rhinitis compared to patients with asthma or rhinitis alone. We examined 878 patients: 182 with asthma, 362 with rhinitis and 334 with both asthma and rhinitis. All had a clinical interview concerning severity of symptoms, treatment, and quality of life, a skin prick test, a lung function test and a bronchial provocation with methacholine. Patients with both asthma and rhinitis had less severe asthma based on the frequency of respiratory symptoms compared to patients with asthma alone (55%vs 66%P = 0.01). On the contrary, they were more airway responsive (P < 0.05) and had more perennial allergy (P < 0.001). Asthmatics had poor perception of the general health, independent of rhinitis (P < 0.001). No differences were found in asthma-specific quality of life, whereas rhinitis-specific quality of life was worse in those with both asthma and rhinitis compared to those with rhinitis alone (P < 0.01). Subjects with both diseases were undertreated in 85% of the cases. We encourage ...Continue Reading
References
Feb 1, 1987·Allergy·S DreborgO Zetterström
Oct 1, 1983·Thorax·K YanA J Woolcock
Feb 1, 1994·American Journal of Respiratory and Critical Care Medicine·J BousquetF B Michel
Jan 15, 1999·Epidemiology·L SheppardJ Q Koenig
Mar 27, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·R M Sly
Aug 19, 1999·The Journal of Allergy and Clinical Immunology·E F JuniperJ N Roberts
Nov 26, 1999·The European Respiratory Journal·C S Ulrik, V Backer
Oct 13, 2000·American Journal of Respiratory and Critical Care Medicine·B LeynaertF Neukirch
Jan 11, 2001·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·J A WinderJ W Brunn
Aug 9, 2001·The European Respiratory Journal·D FuscoC A Perucci
Jun 23, 2005·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J BousquetL Bjermer
Jul 12, 2005·Respiratory Medicine·Hendrik NolteVibeke Backer
Sep 20, 2005·Health and Quality of Life Outcomes·Elizabeth F JuniperElisabeth Ståhl
Jun 21, 2007·Allergy·E MølgaardV Backer
Jul 11, 2007·Allergy and Asthma Proceedings·Vibeke BackerPeter P Plaschke
Sep 13, 2007·Inhalation Toxicology·Jung-Il Choi, Chong S Kim
Jan 2, 2008·The European Respiratory Journal·E D BatemanH J Zar
Mar 26, 2008·Allergy·J BousquetUNKNOWN AllerGen
Mar 3, 2009·The European Respiratory Journal·R DalesP J Villeneuve
Citations
Dec 12, 2012·Cerebral Cortex·Vitaly NapadowFlorian Pfab
Oct 3, 2012·Allergy·P W HellingsJ Bousquet
Apr 18, 2013·Allergy·S LohiaZ M Soler
Mar 18, 2017·Allergy·P W HellingsUNKNOWN ARIA and EPOS working groups
Mar 9, 2017·PLoS Genetics·Dirk SmithKari Stefansson
Jul 19, 2018·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Katie Bonner, Graham Roberts
Sep 1, 2019·The Annals of Otology, Rhinology, and Laryngology·GuanYang Kang
Sep 13, 2019·American Journal of Rhinology & Allergy·GuanYang Kang
Sep 13, 2019·Allergy·Xinni XuDe Yun Wang