Rhino-sinus involvement in children with obstructive sleep apnea syndrome.

Pediatric Pulmonology
Raanan ArensKeivan Shifteh

Abstract

Obstructive sleep apnea syndrome (OSAS) is commonly associated with adenotonsillar hypertrophy. We hypothesized that respiratory perturbations extend to other regions of the upper respiratory tract in such children, particularly to rhino-sinus regions. A prospective case control study using Magnetic Resonance Imaging (MRI) of the upper airway and surrounding tissues of OSAS and controls. Magnetic resonance imaging was used to evaluate radiographic changes within the: paranasal sinuses, middle ear and mastoid air cells, and the nasal passages. We studied 54 OSAS (age 5.7 ± 3.0 years) and 54 controls (age 6.2 ± 2.0 years, P = NS). Children with OSAS had significantly more opacification of: maxillary sinuses (P < 0.05), sphenoid sinuses (P < 0.01), and mastoid air cells (P < 0.01). They also had significantly more: middle ear effusions, (P < 0.001), prominence of inferior nasal turbinate(s) (P < 0.05), and deviation of the nasal septum (P < 0.05). Childhood OSAS is associated with a wide range of upper respiratory tract perturbations and is not limited to adenoid and tonsillar hypertrophy.

References

Nov 1, 1992·The American Review of Respiratory Disease·C L MarcusS L Ward
Sep 1, 1985·The Laryngoscope·J J Principato, P Wolf
Jul 1, 1984·The Journal of Pediatrics·R BrouiletteC Hunt
Feb 1, 1996·American Journal of Respiratory and Critical Care Medicine
Jul 13, 2001·The Journal of Allergy and Clinical Immunology·G Lack
Aug 25, 2001·American Journal of Respiratory and Critical Care Medicine·R ArensA I Pack
Jul 20, 2002·International Journal of Pediatric Otorhinolaryngology·Maurizio RizziMargherita Sergi
Aug 5, 2003·Journal of Applied Physiology·R F FregosiA Gmitro
Jan 24, 2004·The Journal of Laryngology and Otology·Wye-Keat LimKevin J Kane
Jun 4, 2004·The Annals of Otology, Rhinology & Laryngology. Supplement·S James Zinreich
May 10, 2005·American Journal of Respiratory and Critical Care Medicine·Aviv D GoldbartDavid Gozal
Sep 20, 2005·International Journal of Pediatric Otorhinolaryngology·S Cengel, M U Akyol
Nov 7, 2006·American Journal of Otolaryngology·Nithin D Adappa, James M Coticchia
Mar 6, 2007·The Laryngoscope·Chi-Che HuangJoseph Tung-Chieh Chang
Sep 28, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Richard M RosenfeldDavid L Witsell
Sep 11, 2007·Sleep Medicine·David GozalLeila Kheirandish-Gozal
Oct 2, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Claire HopkinsPeter Brown
Oct 9, 2007·Sleep Medicine·David GozalEbrahim Kheirandish
Apr 19, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M G Stewart
Jul 4, 2008·Pediatrics·Leila Kheirandish-Gozal, David Gozal
Aug 30, 2008·International Journal of Pediatric Otorhinolaryngology·Scott E Brietzke, Matthew T Brigger
Sep 16, 2008·International Journal of Pediatric Otorhinolaryngology·Kwang Soo ShinJin Hyeok Jeong
Apr 22, 2009·American Journal of Rhinology & Allergy·Harrison W Lin, Neil Bhattacharyya
Sep 2, 2009·American Journal of Otolaryngology·Chi-Che HuangJoseph Tung-Chieh Chang

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Citations

May 24, 2011·Pediatric Clinics of North America·Manisha Witmans, Rochelle Young
Nov 3, 2010·International Journal of Pediatric Otorhinolaryngology·S TorrettaL Pignataro
Aug 1, 2012·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Gualtiero LeoCristoforo Incorvaia
Aug 24, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Alessandro CazzavillanGiovanni Passalacqua
Sep 3, 2010·Pediatric Pulmonology·David Gozal
Mar 13, 2014·The Laryngoscope·Sanghun SinRaanan Arens
Jun 15, 2015·Seminars in Pediatric Neurology·Fahed HakimDavid Gozal
Jan 23, 2020·The Journal of Laryngology and Otology·O J UngarO Handzel
Jun 20, 2020·Ear, Nose, & Throat Journal·Omer J UngarOphir Handzel

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