PMID: 9438836Feb 7, 1998Paper

Rho GTPases and the actin cytoskeleton

Science
A Hall

Abstract

The actin cytoskeleton mediates a variety of essential biological functions in all eukaryotic cells. In addition to providing a structural framework around which cell shape and polarity are defined, its dynamic properties provide the driving force for cells to move and to divide. Understanding the biochemical mechanisms that control the organization of actin is thus a major goal of contemporary cell biology, with implications for health and disease. Members of the Rho family of small guanosine triphosphatases have emerged as key regulators of the actin cytoskeleton, and furthermore, through their interaction with multiple target proteins, they ensure coordinated control of other cellular activities such as gene transcription and adhesion.

References

Nov 24, 1995·The Journal of Biological Chemistry·S BagrodiaR A Cerione
Nov 1, 1995·Molecular and Cellular Biology·R Khosravi-FarC J Der
Mar 1, 1995·Molecular Biology of the Cell·K PestonjamaspE J Luna
Mar 30, 1995·Nature·R G QiuM Symons
May 25, 1995·Nature·F MichielsJ G Collard
May 23, 1995·Proceedings of the National Academy of Sciences of the United States of America·L StowersJ Chant
Nov 1, 1993·Zygote : the Biology of Gametes and Early Embryos·I MabuchiS Narumiya
May 1, 1996·The Journal of Cell Biology·A M Murphy, D J Montell
Aug 23, 1996·The Journal of Biological Chemistry·M AmanoK Kaibuchi
Oct 1, 1996·Current Opinion in Cell Biology·O HuberR Kemler
Nov 22, 1996·The Journal of Biological Chemistry·H KatohA Ichikawa
Dec 1, 1996·Molecular and Cellular Biology·D J SulcinerT Finkel
Jan 1, 1997·Current Biology : CB·D N DrechselM Glotzer
Feb 1, 1997·Current Opinion in Genetics & Development·E LebererM Whiteway
Feb 24, 1997·Biochemical and Biophysical Research Communications·B BrennerO Linderkamp
May 15, 1997·Nature·D I StruttM Mlodzik

❮ Previous
Next ❯

Citations

Dec 19, 1998·Microscopy Research and Technique·A WellsH Shiraha
Dec 19, 1998·Microscopy Research and Technique·J A Greenwood, J E Murphy-Ullrich
Oct 3, 1999·Microscopy Research and Technique·I SpectorM R Bubb
Oct 3, 1999·Microscopy Research and Technique·J SmallK I Anderson
Oct 3, 1999·Microscopy Research and Technique·H MarutaM Nur-E-Kamal
Oct 3, 1999·Microscopy Research and Technique·P DefilippiG Tarone
Oct 19, 1999·Microscopy Research and Technique·J H Henson
Oct 19, 1999·Microscopy Research and Technique·A S DePina, G M Langford
Dec 22, 1999·Cell Motility and the Cytoskeleton·A WellsD A Lauffenburger
Feb 5, 2000·Cell Motility and the Cytoskeleton·N L Freeman, J Field
Feb 7, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·H A Müller
May 24, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·L L Dobens, L A Raftery
Mar 21, 2000·Journal of Neuroscience Research·A RenaudinL McKerracher
Aug 10, 1999·Journal of Cellular Biochemistry·P M GhoshJ I Kreisberg
Jul 14, 1999·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·P G Allen, J V Shah
Nov 1, 2000·Cell Motility and the Cytoskeleton·N Osherov, G S May
Dec 22, 2000·Cell Motility and the Cytoskeleton·A Pendleton, A Koffer
Jul 25, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·J L GorskiZ Liu
Jan 9, 2001·Journal of Cellular Physiology·A KhamessanR M Johnstone
Jul 6, 2000·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·R A Firtel, C Y Chung
Jan 29, 2002·European Journal of Immunology·Silvia ValensinCosima T Baldari
Jan 10, 2002·Annals of Neurology·Peter HederaJohn K Fink
Jan 10, 2002·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Jennifer C Fletcher
Sep 5, 2002·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Hwan Tae ParkYi Rao
Dec 18, 2001·Cell Motility and the Cytoskeleton·B Safiejko-Mroczka, P B Bell
Jul 12, 2002·Developmental Dynamics : an Official Publication of the American Association of Anatomists·A Sue MenkoMaria A Kukuruzinska
Apr 18, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·A S MenkoM A Kukuruzinska
Apr 18, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·C SchmidtK Patel
Dec 18, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·R MaddalaP V Rao
Jan 5, 2002·International Journal of Cancer. Journal International Du Cancer·Teruo IwasakiHitoshi Akedo
Oct 6, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·R G RussellH A Fleisch

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.