PMID: 9694808DOI: 10.1074/jbc.273.33.20685Aug 8, 1998Paper

Rho GTPases.

The Journal of Biological Chemistry
D J Mackay, Alan Hall

Abstract

No abstract listed.

References

Intracellular localization of the P21rho proteins

Nov 1, 1992·The Journal of Cell Biology·P AdamsonA Hall

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors.

Aug 7, 1992·Cell·A J Ridley, A Hall

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling.

Aug 7, 1992·Cell·A J RidleyA Hall

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

Oct 17, 1991·Nature·A AboA W Segal

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation.

Nov 24, 1995·The Journal of Biological Chemistry·S BagrodiaR A Cerione

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Apr 7, 1995·Cell·C D Nobes, A Hall

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly.

Oct 20, 1995·The Journal of Biological Chemistry·A M BuhlG L Johnson

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

Oct 13, 1995·The Journal of Biological Chemistry·S ZhangG M Bokoch

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

Jun 30, 1995·Cell·O A CosoJ S Gutkind

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Jun 30, 1995·Cell·A MindenM Karin

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

Jun 30, 1995·Cell·C S HillR Treisman

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

Sep 1, 1995·Science·M F OlsonA Hall

Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

Aug 25, 1995·Cell·J H HartwigT P Stossel

An essential role for Rac in Ras transformation

Mar 30, 1995·Nature·R G QiuM Symons

Direct involvement of the small GTP-binding protein Rho in lbc oncogene function.

Apr 21, 1995·The Journal of Biological Chemistry·Y ZhengD Toksoz

A role for Rac in Tiam1-induced membrane ruffling and invasion

May 25, 1995·Nature·F MichielsJ G Collard

Multiple Ras functions can contribute to mammalian cell transformation

Feb 24, 1995·Cell·M A WhiteM H Wigler

The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts.

Apr 1, 1995·Molecular and Cellular Biology·R KozmaL Lim

The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

Nov 4, 1994·Cell·L D ChongM A Schwartz

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

Jan 6, 1994·Nature·E ManserL Lim

The biochemical basis of the NADPH oxidase of phagocytes

Feb 1, 1993·Trends in Biochemical Sciences·A W Segal, A Abo

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

Mar 8, 1996·Cell·M SymonsA Abo

Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

Jun 6, 1996·Nature·A P Gilmore, K Burridge

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

Jul 12, 1996·Science·K KimuraK Kaibuchi

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase).

Aug 23, 1996·The Journal of Biological Chemistry·M AmanoK Kaibuchi

The Dbl family of oncogenes

Apr 1, 1996·Current Opinion in Cell Biology·R A Cerione, Y Zheng

Regulation of transcription by MAP kinase cascades

Apr 1, 1996·Current Opinion in Cell Biology·R Treisman

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

Jan 1, 1996·Current Biology : CB·P AspenströmA Hall

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

May 1, 1996·Current Biology : CB·J L BrownJ Chant

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton.

Oct 1, 1996·Molecular and Cellular Biology·T LeungL Lim

Purification and identification of FOAD-II, a cytosolic protein that regulates secretion in streptolysin-O permeabilized mast cells, as a rac/rhoGDI complex

Mar 1, 1996·Molecular Biology of the Cell·A J O'SullivanB D Gomperts

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

Nov 1, 1996·Cell·N LamarcheA Hall

Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus.

Oct 25, 1996·The Journal of Biological Chemistry·J W EricksonR A Cerione

RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

Nov 22, 1996·Science·T JonesonL Van Aelst

Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family.

Nov 1, 1996·The Journal of Biological Chemistry·H TeramotoJ S Gutkind

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation.

Dec 1, 1996·Molecular and Cellular Biology·D J SulcinerT Finkel

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

Dec 1, 1996·Current Biology : CB·M F OlsonA Hall

ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transduction

Feb 1, 1997·Current Opinion in Cell Biology·S Tsukita, S Yonemura

Pheromone signalling and polarized morphogenesis in yeast

Feb 1, 1997·Current Opinion in Genetics & Development·E LebererM Whiteway

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways.

Mar 1, 1997·Molecular and Cellular Biology·J K WestwickC J Der

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

Feb 28, 1997·Science·M AmanoK Kaibuchi

p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

Mar 10, 1997·FEBS Letters·T IshizakiS Narumiya

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

Jun 2, 1997·The EMBO Journal·N WatanabeS Narumiya

Coupling of Jun amino-terminal kinase and Decapentaplegic signaling pathways in Drosophila morphogenesis

Jul 1, 1997·Genes & Development·B Glise, S Noselli

Regulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42

Jul 28, 1997·The Journal of Cell Biology·S H ZigmondP N Devreotes

Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization

Aug 25, 1997·The Journal of Cell Biology·L M Machesky, A Hall

Rho- and rac-dependent assembly of focal adhesion complexes and actin filaments in permeabilized fibroblasts: an essential role for ezrin/radixin/moesin proteins

Aug 25, 1997·The Journal of Cell Biology·D J MackayA Hall

Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein.

Sep 12, 1997·The Journal of Biological Chemistry·K TakahashiY Takai

Rho GTPases and signaling networks

Oct 6, 1997·Genes & Development·L Van Aelst, C D'Souza-Schorey

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

Nov 14, 1997·Nature·M UehataS Narumiya

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Citations

RHO GTPases in the control of cell morphology, cell polarity, and actin localization in fission yeast

Oct 3, 1999·Microscopy Research and Technique·M ArellanoP Pérez

Nitric oxide induces dose-dependent CA(2+) transients and causes temporal morphological hyperpolarization in human neutrophils

Feb 1, 2000·Journal of Cellular Physiology·V M LoittoK E Magnusson

Suppression of malignant growth potentials of v-Src-transformed human gallbladder epithelial cells by adenovirus-mediated dominant negative H-Ras

Mar 29, 2000·Journal of Cellular Physiology·Y TokumitsuY Niho

Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters

May 23, 2000·Molecular Carcinogenesis·M G Kazanietz

Membrane ruffling, macropinocytosis and antigen presentation in the absence of gelsolin in murine dendritic cells

Nov 11, 1999·European Journal of Immunology·M A WestC Watts

Mutant Rac1B expression in Dictyostelium: effects on morphology, growth, endocytosis, development, and the actin cytoskeleton

Aug 30, 2000·Cell Motility and the Cytoskeleton·S J PalmieriE J Luna

p75 neurotrophin receptor signaling: mechanisms for neurotrophic modulation of cell stress?

Jul 19, 2000·Journal of Neuroscience Research·R T Dobrowsky, B D Carter

Proteomics of rat liver Golgi complex: minor proteins are identified through sequential fractionation

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Understanding Rho/Rac biology in T-cells using animal models

Jul 12, 2002·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Xosé R Bustelo

Tyrosine phosphorylation of p190 RhoGAP by Fyn regulates oligodendrocyte differentiation

Sep 6, 2001·Journal of Neurobiology·R M WolfM D Resh

Helicobacter pylori induces formation of stress fibers and membrane ruffles in AGS cells by rac activation

Mar 1, 2000·Biochemical and Biophysical Research Communications·R PalovuoriT J Karttunen

Up-regulation of p21- and RhoA-activated protein kinases in human pregnant myometrium

Mar 10, 2000·Biochemical and Biophysical Research Communications·F MooreA López Bernal

Activation of MMP-2 by Clostridium difficile toxin B in bovine smooth muscle cells

Oct 12, 2000·Biochemical and Biophysical Research Communications·T KoikeA Iguchi

Constitutively activated Rho guanosine triphosphatases regulate the growth and morphology of hairy cell leukemia cells

May 7, 2003·International Journal of Hematology·Xian ZhangYuzuru Kanakura

Development and differentiation of the intestinal epithelium

Aug 29, 2003·Cellular and Molecular Life Sciences : CMLS·P de Santa BarbaraD J Roberts

Prognostic significance of RACGAP1 mRNA expression in high-risk early breast cancer: a study in primary tumors of breast cancer patients participating in a randomized Hellenic Cooperative Oncology Group trial

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Mechanisms associated with Acanthamoeba castellanii (T4) phagocytosis

Jun 9, 2005·Parasitology Research·Selwa AlsamNaveed Ahmed Khan

Regulation of apoptosis by peptides of fibronectin in human monocytes

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Morphological alterations and cell death provoked by the branched-chain alpha-amino acids accumulating in maple syrup urine disease in astrocytes from rat cerebral cortex

Sep 1, 2005·Cellular and Molecular Neurobiology·Cláudia FunchalRegina Pessoa-Pureur

Activation of RhoA in alcohol-induced intestinal barrier dysfunction

Jan 31, 2013·Inflammation·Jing TongBingyuan Wang

Mathematical model for spatial segregation of the Rho-family GTPases based on inhibitory crosstalk

Apr 26, 2007·Bulletin of Mathematical Biology·Alexandra JilkineLeah Edelstein-Keshet

Altered expression of the small guanosine triphosphatase RhoA in human temporal lobe epilepsy.

Feb 9, 2010·Journal of Molecular Neuroscience : MN·Jie YuanXue-feng Wang

The role of Rho GTPases and SNAREs in mediator release from granulocytes

Jun 14, 2005·Pharmacology & Therapeutics·Paige Lacy

Formin proteins: a domain-based approach

Jun 14, 2005·Trends in Biochemical Sciences·Henry N Higgs

Translating tissue culture results into animal models: the case of Salmonella typhimurium

Dec 9, 2003·Trends in Microbiology·Bryan P Hurley, Beth A McCormick

Divergence and complexities in DAG signaling: looking beyond PKC

Nov 11, 2003·Trends in Pharmacological Sciences·ChengFeng Yang, Marcelo G Kazanietz

Characterization of the interactions between the small GTPase RhoA and its guanine nucleotide exchange factors

Nov 9, 2002·Analytical Biochemistry·Ying-Cai TanZhi-Xin Wang

Deactivation of ROCK-II by Y-27632 enhances basolateral pancreatic enzyme secretion and acute pancreatitis induced by CCK analogues

May 15, 2003·Biochemical and Biophysical Research Communications·Kazushige KusamaKeiji Mitamura

A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation

Feb 20, 2003·Developmental Biology·Luc PoitrasTom Moss

Atorvastatin limits the pro-inflammatory response of rat aortic smooth muscle cells to thrombin

Aug 19, 2003·European Journal of Pharmacology·Mounsif HalouiJean Baptiste Michel

Syndecan-1-mediated cell spreading requires signaling by alphavbeta3 integrins in human breast carcinoma cells

May 17, 2003·Experimental Cell Research·DeannaLee M Beauvais, Alan C Rapraeger

PAK interacts with NCK and MLK2 to regulate the activation of jun N-terminal kinase

May 20, 2003·FEBS Letters·Luc PoitrasTom Moss

Increased RhoA translocation in renal cortex of diabetic rats

Apr 23, 2003·Life Sciences·Amber R MasseyJiping Tang

The Rho-ADP-ribosylating C3 exoenzyme from Clostridium botulinum and related C3-like transferases

Oct 12, 2001·Toxicon : Official Journal of the International Society on Toxinology·C Wilde, K Aktories

Lipid kinases are novel effectors of the GTPase Rac1

Sep 2, 1999·Advances in Enzyme Regulation·C L CarpenterJ Hartwig

Chronic exposure to TXA2 increases expression of ROCKI in human myometrial cells

May 17, 2003·Prostaglandins & Other Lipid Mediators·Frances Moore, Andrés López Bernal

Regulators of G-protein signalling: multifunctional proteins with impact on signalling in the cardiovascular system

Feb 1, 2003·Pharmacology & Therapeutics·Thomas Wieland, Clemens Mittmann

Developmental regulation of FERM domain including guanine nucleotide exchange factor gene expression in the mouse brain

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Clustering of inhibitory neurotransmitter receptors at developing postsynaptic sites: the membrane activation model

Aug 15, 2000·Trends in Neurosciences·M Kneussel, H Betz

Cellular and molecular features of axon collaterals and dendrites

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Expression of FERM domain including guanine nucleotide exchange factor mRNA in adult rat brain

Jun 28, 2003·Brain Research. Molecular Brain Research·Tomas MaduraMasaya Tohyama

Modulation of tight junction function by G protein-coupled events

Jun 16, 2000·Advanced Drug Delivery Reviews·A M HopkinsA Nusrat

Insight in the exocytotic process in chromaffin cells: regulation by trimeric and monomeric G proteins

Jun 24, 2000·Biochimie·N VitaleM F Bader

The characterization of phospholipase D in FRTL-5 thyroid cells

Sep 23, 2000·Molecular and Cellular Endocrinology·M A DevlinJ Ginsberg

The marine compound spisulosine, an inhibitor of cell proliferation, promotes the disassembly of actin stress fibers

Apr 8, 2000·Cancer Letters·R CuadrosJ Avila

Bacterial protein toxins targeting rho GTPases

Jun 27, 2000·FEMS Microbiology Letters·M LermK Aktories

Characterization of a Rab11 homologue in Trypanosoma cruzi

Feb 17, 2000·Gene·S M Mauricio de MendoncaU Gazos Lopes

Rescue of auditory hair cells from aminoglycoside toxicity by Clostridium difficile toxin B, an inhibitor of the small GTPases Rho/Rac/Cdc42

Oct 4, 2002·Hearing Research·Daniel BodmerAllen Ryan

Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha

Oct 24, 2003·Free Radical Biology & Medicine·Ramandeep RattanInderjit Singh

Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinase-dependent pathways

Oct 25, 2003·Cellular Signalling·Raymond E Menard, Raymond R Mattingly

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