Rhodium at the chemistry-biology interface

Dalton Transactions : an International Journal of Inorganic Chemistry
Jun Ohata, Zachary T Ball

Abstract

As a rare element with no known natural biological function, rhodium has a limited history in biological chemistry and chemical biology. However, rhodium complexes have unique structure and reactivity attributes, and chemists have increasingly used these attributes to probe and perturb living systems. This brief review focuses on recent advances in the use of rhodium complexes in biological contexts, including medicinal chemistry, protein science, and chemical biology. In particular, we highlight both structure- and reactivity-driven approaches to biological probes and discuss how coordination environment affects molecular properties in a biological environment.

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Citations

May 7, 2020·Chemistry : a European Journal·María Galiana-CameoRicardo Castarlenas
Mar 14, 2021·European Journal of Medicinal Chemistry·Marzieh SohrabiMohammad Mahdavi
Jan 29, 2020·Cell Chemical Biology·Hiroyuki KojimaToshimasa Itoh
Aug 8, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Qi SunQianling Zhang

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Methods Mentioned

BETA
X-ray
glycosylation

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