Rhodium-Catalyzed/Copper-Mediated Tandem C(sp(2))-H Alkynylation and Annulation: Synthesis of 11-Acylated Imidazo[1,2-a:3,4-a']dipyridin-5-ium-4-olates from 2H-[1,2'-Bipyridin]-2-ones and Propargyl Alcohols

Organic Letters
Ting LiFei Pan

Abstract

A rhodium-catalyzed/copper-mediated tandem C(sp(2))-H alkynylation and intramolecular annulation of 2H-[1,2'-bipyridin]-2-ones with propargyl alcohols for the synthesis of 11-acylated imidazo[1,2-a:3,4-a']dipyridin-5-ium-4-olates is described.

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Citations

Jul 16, 2016·Organic Letters·Wataru MiuraMasahiro Miura
Apr 28, 2017·The Journal of Organic Chemistry·Wataru MiuraMasahiro Miura
Jun 18, 2017·Organic & Biomolecular Chemistry·K Anil KumarParthasarathi Das
Mar 27, 2018·Chemistry, an Asian Journal·Lucien D Caspers, Boris J Nachtsheim
Jul 24, 2018·Chemical Society Reviews·Carlo SambiagioMichael Schnürch

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