Rhodium(iii)-catalyzed unreactive C(sp3 )-H alkenylation of N-alkyl-1H-pyrazoles with alkynes

Organic & Biomolecular Chemistry
Tongyu LiBolin Zhu

Abstract

The first example of pyrazole-directed rhodium(iii)-catalyzed unreactive C(sp3)-H alkenylation with alkynes has been described, which showed a relatively broad substrate scope with good functional group compatibility. Moreover, we demonstrated that the transitive coordinating center pyrazole could be easily removed under mild conditions.

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