Rhodotorula mucilaginosa outbreak in neonatal intensive care unit: microbiological features, clinical presentation, and analysis of related variables

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
R PerniolaR Longo

Abstract

Reported here are the features of a Rhodotorula mucilaginosa outbreak that occurred in a neonatal intensive care unit. Over a period of 19 days, clinical and laboratory signs of sepsis appeared in four premature infants carrying indwelling vascular catheters. After bloodstream infection with R. mucilaginosa was ascertained, the patients underwent amphotericin B therapy and recovered completely. In a retrospective case-control study, the variables displaying a statistical difference between case and control-group neonates were birth weight, gestational age, duration of parenteral nutrition, duration of antibiotic therapy and prophylactic administration of fluconazole. To our knowledge, this is the first reported outbreak caused by yeasts of the Rhodotorula genus.

References

Apr 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·T E KiehnD Armstrong
Dec 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·T E Kiehn, D Armstrong
Oct 1, 1995·Clinical Microbiology Reviews·K C Hazen
Dec 1, 1995·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·M E HaganM Nelson
Apr 16, 1999·The Journal of Hospital Infection·V KrcmeryD W Denning
Jul 10, 1999·Clinical Microbiology Reviews·J GuarroA M Stchigel
Aug 22, 2000·Archives of Disease in Childhood. Fetal and Neonatal Edition·N Modi, R Carr
Jan 5, 2002·The New England Journal of Medicine·D KaufmanL G Donowitz
Apr 7, 1962·JAMA : the Journal of the American Medical Association·P F SHELBURNE, R J CAREY
Feb 8, 2005·The Journal of Antimicrobial Chemotherapy·Alicia Gomez-LopezManuel Cuenca-Estrella

❮ Previous
Next ❯

Citations

Jun 5, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E C RepettoF Castelli
Jan 31, 2009·Medical Mycology·Gisele M Duboc De AlmeidaMarcelo N Burattini
Apr 26, 2007·AIDS·Ravinder KaurSatish Kumar Agarwal
May 2, 2008·Current Opinion in Infectious Diseases·Walter ZinggDidier Pittet
Dec 4, 2012·Nutrients·Walter ZinggMaria Martin
Jan 23, 2013·Microbial Biotechnology·Jonathan A CrayJohn E Hallsworth
Feb 1, 2011·The British Journal of Dermatology·T JaegerM D Anliker
Mar 14, 2007·The Journal of Hospital Infection·S Srivastava, N Shetty
Oct 24, 2012·Interdisciplinary Perspectives on Infectious Diseases·Fernanda Wirth, Luciano Z Goldani
Apr 20, 2016·Journal de mycologie médicale·R GuidaraA Ayadi
Oct 10, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M C ArendrupUNKNOWN European Confederation of Medical Mycology
Sep 30, 2018·Mycoses·Petros IoannouGeorge Samonis
Jan 22, 2010·Critical Reviews in Microbiology·Michael A Pfaller, Daniel J Diekema
Jul 6, 2010·Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih·Wen-jun TuJames Jian Ho
Mar 19, 2020·Emerging Infectious Diseases·Anuradha ChowdharyJacques F Meis
May 12, 2012·Mycopathologia·Anastasia SpiliopoulouMyrto Christofidou
May 1, 2021·Pathogens·Kamila KuleszaŁukasz Stępień
Oct 12, 2016·Microbiology Spectrum·Sean X Zhang, Nathan P Wiederhold

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Luciano W LunardiLuciano Z Goldani
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
V Lo ReI Nachamkin
Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Jesús Monterrubio VillarJuan Diego Jiménez Delgado
© 2021 Meta ULC. All rights reserved