PMID: 6989336Feb 1, 1980Paper

Ribonuclease activity during G1 arrest of the yeast Saccharomyces cerevisiae

Archives of Microbiology
E S McFarlane

Abstract

When cells of the yeast, Saccharomyces cerevisiae, were deprived of nitrogen, a condition leading to G1 arrest, there was an immediate increase in the levels of total ribonuclease (RNase) activity within these cells. During starvation, only the cells arrested in G1 showed increased RNase activity. Although the RNase activities of extracts of starved and actively growing cells were similarly influenced by pH, the activities of starved cells were less stable on both storage and heating. Differences were also noted in substrate specificity. The results of this study suggest that arrest within G1 may increase RNase activity. However, all RNases did not appear to be influenced equally, since the total pool of RNase activity from log phase and G1 arrested cells showed differences in stability and substrate specificity.

References

Nov 3, 1975·Biochemical and Biophysical Research Communications·K K Reddi
Mar 1, 1977·Experimental Cell Research·G C JohnstonL H Hartwell
Nov 1, 1977·Journal of Bacteriology·G C JohnstonS McFarlane
Feb 5, 1973·Journal of Molecular Biology·R W ShulmanJ R Warner
Oct 1, 1963·Journal of Biochemistry·Y OHTAKAT SAKAI

❮ Previous
Next ❯

Citations

Apr 1, 1985·Journal of Steroid Biochemistry·K E Penttilä, P H Mäenpää
Dec 15, 1983·European Journal of Biochemistry·D J Mead, S G Oliver
Mar 10, 2006·Microbiology and Molecular Biology Reviews : MMBR·Gang RenAlan L Munn
Jan 18, 2019·Nature·Jeffrey T MorganDavid P Bartel

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.