PMID: 6991870Jan 1, 1980Paper

Ribosomal protein modification in Escherichia coli. II. Studies of a mutant lacking the N-terminal acetylation of protein S18

Molecular & General Genetics : MGG
K Isono, S Isono

Abstract

A mutant of Escherichia coli K12 has been isolated which shows an alteration in the ribosomal protein S18. Genetic analyses have revealed that the mutation causing this alteration maps at 99.3 min of the E. coli genetic map, between dnaC and deo. This indicated that the mutation has occurred in a gene different from the structural gene for this protein which has been located at 94 min. From the N-terminal amino acid sequence analysis it is concluded that the mutation has resulted in loss of the N-terminal acetyl group of this protein. The gene which is affected in this mutant is termed rimI that most likely specifies an enzyme acetylating the N-terminal alanine of protein S18. The mutation does not affect the acetylation of two other ribosomal proteins, S5 and L12, both of which are known to be acetylated in wild-type E. coli K12.

References

Apr 29, 1977·Molecular & General Genetics : MGG·K IsonoS Isono
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Jun 1, 1963·Journal of Bacteriology·H E UMBARGERP M SIU

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Citations

Sep 7, 2007·Microbiology and Molecular Biology Reviews : MMBR·Magdalena Kaczanowska, Monica Rydén-Aulin
Jul 4, 2008·Protein Science : a Publication of the Protein Society·Matthew W VettingJohn S Blanchard
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Jul 31, 2020·Microbiology and Molecular Biology Reviews : MMBR·Mario ZamoraAlan J Wolfe
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Apr 21, 2007·Biochemical and Biophysical Research Communications·Lin MiaoHuipeng Chen

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