Ridge preservation following tooth extraction using mineralized freeze-dried bone allograft compared to mineralized solvent-dehydrated bone allograft: A randomized controlled clinical trial

Journal of Periodontology
Patrick J Corning, Brian L Mealey

Abstract

Freeze dried bone allograft (FDBA) and solvent dehydrated bone allograft (SDBA) are both commonly used in alveolar ridge preservation. Previous studies have suggested SDBA may have advantages over FDBA due to a unique processing method. The primary objective of this study was to histologically compare the healing outcome between FDBA and SDBA when used for ridge preservation. Changes in morphometric ridge parameters were evaluated as a secondary outcome. Forty-four patients requiring extraction and ridge preservation were randomized into two groups: FDBA (control group) or SDBA (test group). Patients returned 12 weeks post-extraction and ridge preservation for implant placement. A bone core was taken in the planned implant osteotomy site and evaluated histomorphometrically to determine the percentage of vital bone, residual graft material, and connective/other tissue. Changes in clinical ridge dimensions were also evaluated for patients in both treatment groups. The FDBA group showed a mean of 24.08% vital bone, 22.96% residual graft material, and 52.95% CT/other. The SDBA group showed a mean of 27.19% vital bone, 23.38% residual graft material, and 49.41% CT/other. No statistical differences were found between groups in the me...Continue Reading

Associated Clinical Trials

References

Mar 1, 1972·Journal of Periodontology·D L WoodL D Rosenfeld
May 25, 2002·The Journal of International Medical Research·E DayiA B Yilmaz
Sep 3, 2008·The Journal of the American Dental Association·Dan HoltzclawDon Callan
Jun 12, 2013·The International Journal of Oral & Maxillofacial Implants·Hsun-Liang ChanHom-Lay Wang
Jul 4, 2013·The International Journal of Periodontics & Restorative Dentistry·Thomas W SterioBrian L Mealey
Oct 26, 2013·Journal of Dental Research·V ChappuisD Buser
Feb 24, 2017·The International Journal of Oral & Maxillofacial Implants·Stefano CorbellaMassimo Del Fabbro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.